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Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 mL dosage, for intramuscular use

CPT4 code

Name of the Procedure:

Influenza Virus Vaccine, Trivalent (IIV3), Split Virus, Preservative-Free, 0.5 mL Dosage for Intramuscular Use
Common name(s): Flu Shot, Trivalent Influenza Vaccine


The trivalent influenza vaccine is an injection given to protect against three different strains of the influenza virus. This preservative-free vaccine is administered into a muscle, usually in the upper arm.


The purpose of the trivalent influenza vaccine is to prevent influenza, commonly known as the flu, and reduce the severity of symptoms in case of infection. The expected outcome is a reduced incidence of flu-related illness, hospitalizations, and complications, particularly in high-risk populations.


  • People aged 6 months and older, especially those at higher risk for flu complications (e.g., elderly, pregnant women, those with chronic medical conditions).
  • Individuals who might transmit the flu to high-risk populations, such as healthcare workers and caregivers.


  • No special preparation is usually required.
  • Inform your healthcare provider of any severe allergies or adverse reactions to previous flu vaccines.
  • Wear loose clothing that allows easy access to the upper arm.

Procedure Description

  1. The healthcare provider will clean the injection site, usually the upper arm, with an antiseptic wipe.
  2. The vaccine is then drawn from a pre-filled syringe into a needle.
  3. The needle is inserted into the muscle, and the vaccine is administered.
  4. The injection site is then covered with a small adhesive bandage, if necessary.


The injection is quick, typically taking just a few minutes.


The procedure is usually performed in a healthcare provider's office, clinic, pharmacy, or sometimes at a workplace or community flu shot clinic.


  • Administered by a trained healthcare professional, such as a nurse or doctor.

Risks and Complications

  • Common: Soreness at the injection site, mild fever, muscle aches.
  • Rare: Allergic reactions, such as rash or difficulty breathing. Severe allergic reactions are extremely rare but need immediate medical attention.


  • Reduces the likelihood of contracting the flu.
  • Decreases the severity of flu symptoms if contracted.
  • Protects individuals and helps in preventing the spread of the virus within the community.


  • Resume normal activities immediately after the vaccination.
  • Some may experience mild side effects like soreness at the injection site or a low-grade fever, which typically resolve within a day or two.
  • Follow any specific instructions given by the healthcare provider and schedule follow-up if advised.


  • Quadrivalent Influenza Vaccine (protects against four strains of the virus).
  • Other forms of the influenza vaccine, such as the live attenuated intranasal vaccine, are options based on age and health status.
  • Alternative methods of prevention include antiviral medications and general health practices like frequent handwashing and avoiding close contact with sick individuals.

Patient Experience

  • The patient will feel a quick pinch or sting when the needle is inserted.
  • Post-injection, minor tenderness or swelling at the site may occur.
  • Most people feel fine immediately after and can continue with everyday activities.
  • Instructions will be given for managing any minor side effects, typically involving over-the-counter pain relief if needed.

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