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Rho(D) immune globulin (RhIg), human, mini-dose, for intramuscular use

CPT4 code

Name of the Procedure:

Rho(D) Immune Globulin (RhIg), Human, Mini-Dose for Intramuscular Use

  • Common Name(s): RhIg Mini-Dose, Rh Immunoglobulin, Anti-D Immunoglobulin
  • Medical Term: Rho(D) Immune Globulin

Summary

Rho(D) Immune Globulin (RhIg) Mini-Dose is an injectable medication given to prevent Rh sensitization. It involves a small dose of immune globulin administered via an intramuscular injection.

Purpose

RhIg Mini-Dose is primarily used to prevent Rh sensitization in Rh-negative individuals exposed to Rh-positive blood. This is crucial for avoiding complications in future pregnancies, such as hemolytic disease of the newborn.

Indications

  • Pregnant Rh-negative women who have given birth to an Rh-positive baby.
  • After a miscarriage, abortion, or ectopic pregnancy.
  • Following invasive procedures during pregnancy like amniocentesis or chorionic villus sampling.
  • In cases of trauma or bleeding during pregnancy.

Preparation

  • No special preparation or fasting is generally required.
  • Inform the healthcare provider about any medications, allergies, or medical conditions.
  • Blood type and antibody screen might be performed to confirm Rh-negative status.

Procedure Description

  1. Consent and Explanation: The healthcare provider explains the procedure, its benefits, and risks.
  2. Preparation: The patient’s skin at the injection site (usually the upper arm or buttock) is cleaned with an antiseptic solution.
  3. Injection: Using a sterile needle and syringe, the RhIg mini-dose is injected intramuscularly.
  4. Post-Injection: The injection site is covered with a bandage, and the patient is monitored for any immediate reactions.

Tools and Equipment:

  • Sterile needle and syringe
  • Antiseptic solution
  • Bandage

Anesthesia or Sedation:

  • None required; it is typically a quick and minimally uncomfortable procedure.

Duration

The entire procedure typically takes about 10 to 15 minutes.

Setting

  • Hospital labor and delivery units
  • Outpatient clinics
  • Doctor's offices

Personnel

  • Registered Nurse (RN)
  • Physician or Specialist (Obstetrician, Hematologist)

Risks and Complications

  • Common Risks: Mild soreness at the injection site, slight fever, redness
  • Rare Risks: Allergic reactions, including anaphylaxis (extremely rare)

Benefits

  • Prevents Rh sensitization
  • Reduces the risk of hemolytic disease in future pregnancies
  • Expected benefits can be realized shortly after administration

Recovery

  • Immediate post-injection care includes monitoring for allergic reactions for about 20 minutes.
  • No significant downtime; patients can usually resume regular activities immediately.
  • Follow-up blood tests might be required to confirm the absence of Rh antibodies.

Alternatives

  • In some cases, expectant management with careful monitoring may be considered, but this carries risks.
  • Blood transfusions for severe cases of Rh sensitization (though preventative measures like RhIg are preferred to avoid such scenarios).

Patient Experience

  • During the procedure: Minor discomfort or pressure at the injection site.
  • After the procedure: Slight soreness at the injection site, manageable with over-the-counter pain medications if necessary.
  • Pain management: Use of cold packs or over-the-counter analgesics for discomfort.

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