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Rabies immune globulin, heat-treated (RIg-HT), human, for intramuscular and/or subcutaneous use

CPT4 code

Name of the Procedure:

Rabies Immune Globulin, Heat-Treated (RIg-HT), Human, for Intramuscular and/or Subcutaneous Use

Summary

Rabies Immune Globulin, Heat-Treated (RIg-HT), is an injection given to people who have been exposed to rabies. The injection provides immediate, short-term protection against the rabies virus until the rabies vaccine starts to work.

Purpose

Medical Condition:
  • Exposure to rabies virus (e.g., through an animal bite).
Goals/Expected Outcomes:
  • To provide immediate protection against rabies.
  • To help prevent the onset of rabies infection.

Indications

Symptoms/Conditions:
  • Exposure to a potentially rabid animal.
  • Bite or scratch from an animal suspected of having rabies.
Patient Criteria:
  • Any person who has been exposed to the rabies virus and has not been previously vaccinated against rabies.

Preparation

Pre-Procedure Instructions:
  • No specific preparation is typically required for this injection.
Diagnostic Tests/Assessments:
  • Wound cleaning and assessment of the exposure incident.

Procedure Description

  1. The healthcare provider will clean the wound area thoroughly.
  2. using sterile procedure and equipment, the RIg-HT is drawn into a syringe.
  3. The injection is administered either intramuscularly (often in the thigh or buttock) or subcutaneously (under the skin), sometimes directly into the wound site.

    Tools and Equipment:
    • Syringe, needle, and the RIg-HT solution.
Anesthesia or Sedation:
  • Usually not required, though local anesthetic may be used in some cases.

Duration

The procedure itself typically takes about 10-20 minutes.

Setting

  • Hospital emergency room or outpatient clinic.

Personnel

  • Performed by a healthcare professional, usually a doctor or nurse.

Risks and Complications

Common Risks:
  • Pain at the injection site.
  • Minor swelling or redness at the injection site.
Rare Risks:
  • Allergic reactions.
  • Fever.
  • Infection at the injection site.
Possible Complications:
  • Hypersensitivity reactions, which can be managed with medications.

Benefits

Immediate protection against the rabies virus is provided, and this helps prevent the onset of rabies, a potentially fatal disease. Benefits are typically realized immediately after administration.

Recovery

Post-Procedure Care:
  • Keep the injection site clean and dry.
  • Monitor for any signs of infection or allergic reaction.
Expected Recovery Time:
  • Minimal; most patients can resume normal activities shortly after the procedure.
Restrictions/Follow-Up:
  • Follow-up appointments may be scheduled to receive the rabies vaccination series.

Alternatives

Other Treatment Options:
  • There are no direct alternatives to Rabies Immune Globulin for immediate post-exposure prophylaxis; without RIg-HT, the rabies vaccine alone may not be as effective initially.
Pros and Cons:
  • RIg-HT: Immediate protection, crucial for preventing rabies after exposure.
  • Rabies Vaccine Alone: Slower onset of action, less effective immediately post-exposure without RIg-HT.

Patient Experience

During the Procedure:
  • Some discomfort or pain during the injection.
After the Procedure:
  • Mild soreness at the injection site.
  • Most patients tolerate the procedure well.
  • Pain management includes over-the-counter pain relievers like acetaminophen or ibuprofen.
Comfort Measures:
  • Applying a cold pack to the injection site can help reduce pain and swelling.

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