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Antibody; Brucella

CPT4 code

Name of the Procedure:

Antibody; Brucella (also known as Brucella Serology or Brucella Antibody Test)


The Brucella Antibody Test is a blood test used to detect antibodies against Brucella bacteria, which are the cause of brucellosis, a zoonotic infection that spreads from animals to humans.


This test is used to diagnose brucellosis, a bacterial infection that can cause fever, joint pain, and fatigue. Identifying the presence of Brucella antibodies helps to confirm the infection and guide appropriate treatment.


  • Persistent fever of unknown origin
  • Unexplained joint or muscle pain
  • Individuals with a history of exposure to infected animals or consuming unpasteurized dairy products
  • Cases where brucellosis is suspected based on clinical symptoms


  • No special preparation is required for this test.
  • Patients may be asked about their medical history and potential exposure to Brucella bacteria.

Procedure Description

  1. A healthcare provider will clean the skin over a vein in the arm.
  2. A needle is inserted into the vein to draw a blood sample.
  3. The blood sample is sent to a laboratory for analysis.
  4. The blood is tested for the presence of antibodies against Brucella bacteria.


The blood draw typically takes around 5-10 minutes. Lab processing takes a few days to a week.


The procedure is done in a healthcare provider’s office, clinic, or hospital laboratory.


  • Phlebotomist or nurse to draw the blood sample
  • Laboratory technician to analyze the sample

Risks and Complications

  • Minor risks associated with blood draw, including bruising, bleeding, or infection at the puncture site
  • Rarely, dizziness or fainting may occur


  • Accurate diagnosis of brucellosis
  • Enables timely and appropriate treatment to avoid complications
  • Helps in tracking and managing the spread of infection


  • No significant recovery period is needed for the blood draw.
  • Patients can typically resume normal activities immediately.


  • Culture of blood, bone marrow, or other body fluids (more invasive and time-consuming)
  • Polymerase chain reaction (PCR) testing for detecting Brucella DNA (less commonly available)

Patient Experience

The blood draw may cause brief discomfort or a pinching sensation. Afterward, patients may experience slight tenderness or bruising at the puncture site, which typically resolves on its own.