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Antibody; Bordetella

CPT4 code

Name of the Procedure:

Antibody; Bordetella (also known as Bordetella Pertussis Antibody Test)


This test measures the level of antibodies in the blood that are directed against Bordetella pertussis, the bacterium that causes whooping cough (pertussis). It involves a simple blood draw to detect if your immune system has produced a response to the bacteria, indicating either past infection or immunization.


The procedure aims to determine if a person has been recently infected with Bordetella pertussis or has immunity due to vaccination. It helps diagnose active or past infection and verifies if an individual has mounted an immune response following vaccination.


  • Persistent cough lasting more than two weeks
  • Exposure to someone with confirmed or suspected whooping cough
  • Symptoms such as severe coughing fits followed by a whooping sound, vomiting, or difficulty breathing
  • To confirm immunity status in individuals, especially healthcare workers or people in close contact with infants


  • No special preparation is usually required.
  • Inform the healthcare provider about all medications and supplements you are taking.
  • Fasting is generally not needed, but follow any specific instructions provided by your healthcare professional.

Procedure Description

  1. A healthcare professional will clean the skin with an antiseptic solution.
  2. An elastic band is tied around the upper arm to fill veins with blood.
  3. A needle is inserted into a vein in the arm to draw a blood sample.
  4. The blood sample is collected into a vial or tube.
  5. The elastic band is removed, and the needle is withdrawn.
  6. A bandage or gauze is applied to stop any bleeding.


The blood draw generally takes about 5-10 minutes.


This test is usually performed in a laboratory, doctor's office, or outpatient clinic.


The procedure is carried out by a trained phlebotomist or nurse.

Risks and Complications

  • Minor risks include bruising, slight bleeding, or infection at the needle site.
  • Rarely, patients might feel dizzy or faint.


  • Helps in early and accurate diagnosis of whooping cough.
  • Confirms immunity status post-vaccination, which is crucial for individuals in high-risk occupations.
  • Allows timely initiation of treatment and preventive measures.


  • Minimal recovery time; you can resume normal activities immediately after the procedure.
  • Keep the puncture site clean and dry.
  • Follow any further instructions provided by the healthcare provider.


  • Polymerase Chain Reaction (PCR) testing for Bordetella pertussis DNA
  • Culture of nasal or throat swabs for Bordetella pertussis bacteria
Pros and Cons of Alternatives:
  • PCR Testing: Faster results but may be more expensive.
  • Culture: Highly specific but takes longer to get results and is less sensitive in later stages of the disease.

Patient Experience

  • The procedure might cause mild discomfort due to the needle insertion.
  • You might experience a slight pinch during the blood draw.
  • Post-drawing, most patients feel fine, though managing minor bruising or tenderness at the puncture site may be necessary.

Pain management and comfort measures include applying an ice pack to the puncture site if needed and keeping the site clean to prevent infection.