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Antibody; Francisella tularensis

CPT4 code

Name of the Procedure:

Antibody Test for Francisella tularensis (Tularemia Antibody Test)

Summary

This test detects antibodies in the blood that are produced in response to an infection caused by Francisella tularensis, the bacterium that causes tularemia. It is a blood test that helps diagnose the presence of tularemia.

Purpose

The test is used to diagnose tularemia, a rare infectious disease. It aims to confirm the presence of antibodies against Francisella tularensis, which helps in the diagnosis and subsequent treatment of the infection.

Indications

  • Symptoms suggestive of tularemia, such as fever, skin ulcers, swollen lymph nodes, and fatigue.
  • Exposure to environments where Francisella tularensis is common, such as contact with wild animals or insect bites.
  • Handling or processing animal products that may be contaminated.

Preparation

  • No special preparation is usually needed.
  • Patients should inform their healthcare provider about any medications or supplements they are taking.
  • Healthcare providers may review medical history and symptoms before the test.

Procedure Description

  1. The healthcare provider will clean the area where the blood will be drawn, usually the inside of the elbow or the back of the hand.
  2. A needle is inserted into a vein to draw a blood sample.
  3. The blood sample is sent to a laboratory for analysis, where it is tested for antibodies against Francisella tularensis.
  4. The results are typically available within a few days.

Duration

The actual blood draw typically takes less than 10 minutes. Laboratory analysis may take several days.

Setting

The blood draw is usually performed in a hospital, outpatient clinic, or laboratory.

Personnel

  • A phlebotomist or a nurse typically performs the blood draw.
  • A laboratory technician or pathologist analyzes the blood sample.
  • A healthcare provider or infectious disease specialist interprets the results.

Risks and Complications

  • Minor pain or discomfort at the injection site.
  • Bruising or bleeding at the blood draw site.
  • Rarely, dizziness or fainting.
  • Risk of infection at the puncture site, which is very low.

Benefits

  • Accurate diagnosis of tularemia.
  • Rapid initiation of appropriate antibiotic treatment if the test is positive.
  • Helps in preventing complications associated with untreated tularemia.

Recovery

  • Minimal recovery time; patients can usually resume normal activities immediately after the blood draw.
  • Follow-up appointments may be scheduled to discuss test results and further treatment, if necessary.

Alternatives

  • Polymerase Chain Reaction (PCR) test for detecting Francisella tularensis DNA.
  • Culture tests involving samples from infected sites.
  • Imaging tests and clinical evaluation for symptoms associated with tularemia.
  • Each alternative has its own advantages and limitations regarding accuracy, availability, and invasiveness.

Patient Experience

  • During the procedure, the patient may feel a small prick or sting when the needle is inserted.
  • Mild discomfort or bruising at the site of blood draw may occur.
  • Anxiety about blood tests or needles can be managed with reassurance and ensuring the patient is comfortable.
  • No significant pain or adverse effects are expected post-procedure.