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Injection, interferon beta-1a, 1 mcg for intramuscular use

HCPCS code

Name of the Procedure:

Injection, interferon beta-1a, 1 mcg for intramuscular use (Q3027)

  • Common Name: Interferon Beta Injection
  • Technical Name: Recombinant Interferon Beta-1a Intramuscular Injection

Summary

This procedure involves administering a small dose of interferon beta-1a via an intramuscular injection. It is a treatment primarily used for certain types of multiple sclerosis, aiming to reduce the frequency and severity of symptoms.

Purpose

Interferon beta-1a is used to:

  • Treat relapsing forms of multiple sclerosis (MS).
  • Decrease the number of relapses in MS patients.
  • Slow down the progression of physical disability in MS.

Indications

  • Diagnosed with relapsing-remitting multiple sclerosis (RRMS).
  • Experiencing frequent flare-ups or exacerbations.
  • Evidence of disease activity on MRI scans.

Preparation

  • No specific fasting required.
  • Inform the healthcare provider of all medications being taken.
  • Blood tests may be required to assess liver function and blood cell counts.

Procedure Description

  1. The healthcare provider will prepare the interferon beta-1a solution.
  2. The injection site, typically the thigh or upper arm, will be disinfected.
  3. Using a sterile syringe, a dose of 1 mcg interferon beta-1a will be drawn.
  4. The provider will then administer the injection intramuscularly.
  5. Post-injection, the site may be massaged gently to aid in absorption.

Equipment:

  • Sterile syringe and needle.
  • Alcohol wipes or antiseptic solution.
  • Interferon beta-1a solution.

Duration

The procedure typically takes around 10-15 minutes.

Setting

Usually performed in an outpatient clinic or healthcare provider’s office.

Personnel

  • Registered Nurse (RN)
  • Medical Doctor (MD) or Nurse Practitioner (NP) for supervision

Risks and Complications

  • Common: Injection site reactions (redness, swelling, pain), flu-like symptoms (fever, chills, fatigue).
  • Rare: Allergic reactions, liver dysfunction, low blood cell counts.
  • Management: Symptomatic treatment for mild reactions, medical intervention for severe complications.

Benefits

  • Reduction in the frequency of MS relapses.
  • Slower progression of physical disability.
  • Improved quality of life.

Recovery

  • Immediate post-procedure care includes monitoring for adverse reactions.
  • Continue with normal activities unless otherwise advised.
  • Follow-up appointments to monitor response and adjust dosage if necessary.

Alternatives

  • Other immunomodulatory treatments for MS, such as:
    • Glatiramer acetate
    • Fingolimod
    • Ocrelizumab
    • Pros: Different mechanisms of action, may be more effective for certain patients.
    • Cons: Different side effect profiles, varying routes of administration and frequency.

Patient Experience

  • During: Mild discomfort or pain at the injection site.
  • After: Possible flu-like symptoms managed with over-the-counter pain relievers and rest.
  • Pain management: Use of analgesics, proper injection technique to minimize discomfort.

Medical Policies and Guidelines for Injection, interferon beta-1a, 1 mcg for intramuscular use

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