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Injection, bivalirudin, 1 mg

HCPCS code

Name of the Procedure:

Injection, Bivalirudin, 1 mg (J0583)

Common Name: Bivalirudin Injection
Technical/Medical Term: Intravenous Bivalirudin Administration

Summary

Bivalirudin injection is a medical procedure where a drug called bivalirudin is administered directly into the bloodstream. Bivalirudin is an anticoagulant, meaning it helps prevent blood clots from forming, which is crucial during specific cardiac procedures like angioplasty.

Purpose

Medical Conditions Addressed: Bivalirudin is primarily used for patients undergoing percutaneous coronary intervention (PCI), including angioplasty, to prevent the formation of blood clots.

Goals/Outcomes: The primary goal is to reduce the risk of blood clot formation during and after PCI procedures, ensuring smoother blood flow and reducing the chances of complications such as heart attacks.

Indications

Specific Symptoms/Conditions: The procedure is indicated for patients undergoing PCI who are at risk of clot formation. It can also be used in patients with heparin-induced thrombocytopenia.

Patient Criteria: Patients with coronary artery disease, those undergoing angioplasty, or those with a history of heparin-induced adverse events are appropriate candidates.

Preparation

Pre-Procedure Instructions:

  • Patients might need to fast for a few hours before the procedure.
  • Adjustments to regular medications should be made as directed by a healthcare provider.
  • Assessments, such as blood tests and heart monitoring, are often required to ensure patient readiness.

Procedure Description

  1. Patient Preparation: The patient is prepped and may receive local or mild sedation depending on the scenario.
  2. Insertion: A healthcare provider inserts an intravenous (IV) line into the patient's vein.
  3. Drug Administration: Bivalirudin is administered through the IV line over a specified period, usually continuously monitored.
  4. Monitoring: Vital signs and clotting function are closely watched throughout the procedure.

Tools/Equipment: Syringe, IV line, infusion pump (if needed).

Anesthesia/Sedation: Usually not required or only mild, based on patient anxiety and overall condition.

Duration

The administration of bivalirudin typically lasts for the duration of the PCI procedure, usually around 1-2 hours, but can be extended based on the patient's condition.

Setting

Typical locations: This procedure is performed in a hospital setting, specifically in the cardiac catheterization lab or intervention suites.

Personnel

Healthcare professionals involved include a cardiologist or interventional radiologist, nursing staff, and potentially an anesthesiologist.

Risks and Complications

Common Risks:

  • Bleeding or bruising at the injection site
  • Allergic reactions

Rare Risks:

  • Severe bleeding
  • Hypotension
  • Anaphylaxis

Management: Any complications are managed with appropriate medical interventions such as anticoagulant reversal agents, additional medications, or supportive care.

Benefits

Expected Benefits: The main benefit is the prevention of blood clot formation during and after angioplasty, which enhances patient safety and outcome success.

Realization Time: Benefits are realized almost immediately, particularly during the procedure, as bivalirudin acts quickly to prevent clots.

Recovery

Post-Procedure Care: Patients are monitored for signs of bleeding and other adverse effects. Regular blood tests may be required to ensure proper coagulation levels.

Recovery Time: Immediate effects are monitored for a few hours post-procedure, with typical recovery extending over a day or two.

Restrictions/Follow-up: Minimal restrictions are typically necessary, and follow-up appointments ensure no delayed adverse effects are present.

Alternatives

Other Treatment Options:

  • Heparin
  • Other anticoagulants like argatroban

Pros and Cons of Alternatives: Heparin is widely used but may cause thrombocytopenia in some patients. Alternative anticoagulants might have different risk profiles or efficacy levels.

Patient Experience

During Procedure: Patients may feel a slight prick during IV insertion and mild discomfort as the drug is administered. Sedation can help ease anxiety.

After Procedure: Some patients might feel mild discomfort at the injection site and should watch for any signs of excessive bleeding or allergic reactions.

Pain Management/Comfort Measures: Minimal pain is expected, managed by the healthcare team through proper technique and, if necessary, mild analgesics.

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