Name of the Procedure:

Respiratory Syncytial Virus (RSV) Monoclonal Antibody, Recombinant, for Intramuscular Use, 50 mg, Each

Summary

This procedure involves administering a monoclonal antibody injection to help prevent severe respiratory syncytial virus (RSV) infections. The injection is given into a muscle (intramuscular), typically in a clinical setting.

Purpose

This procedure is designed to prevent serious RSV infections, particularly in infants and young children who are at high risk. The goal is to provide protective antibodies that help the immune system combat RSV and reduce the severity of the illness.

Indications

• Infants born prematurely (before 35 weeks of gestation)
• Children under two years with chronic lung disease or congenital heart disease
• Infants with weakened immune systems
• Infants and children in high-risk environments or with a history of severe RSV

Preparation

• No specific fasting or preparation for the patient.
• Thorough medical history and physical examination will be conducted.
• Discuss the child's current medications and any allergies with the healthcare provider.

Procedure Description

1. The healthcare provider will prepare the monoclonal antibody solution.
2. The injection site (usually the thigh or upper arm) will be cleaned with an antiseptic.
3. The monoclonal antibody is then injected into the muscle using a syringe.
4. The injection site is monitored for a brief period to check for any immediate reactions.

Duration

The injection itself typically takes just a few minutes, but the entire visit may last about 30 minutes to include preparation and monitoring time.

Setting

The procedure is performed in an outpatient clinic or a doctor's office.

Personnel

• Administered by a nurse or a qualified healthcare provider.
• The prescribing pediatrician or physician may be involved in dosing and oversight.

Risks and Complications

• Pain, redness, or swelling at the injection site
• Fever
• Rash or mild allergic reactions
• Rarely, serious allergic reactions (anaphylaxis)

Management: Most reactions are mild and are managed with over-the-counter medications or simple care at the injection site.

Benefits

• Reduced risk of severe RSV infection.
• Decreased hospitalization rates for RSV-related complications.
• Protective effects last throughout the RSV season.

Recovery

• Most children can return to their regular activities immediately.
• Parents should monitor the injection site and watch for signs of an allergic reaction.
• Follow-up appointments as recommended by the healthcare provider.

Alternatives

• Supportive care if infection occurs (e.g., fluids, oxygen therapy).

• No other preventive RSV-specific antibody treatment available.

  Pros and cons: Preventative injections offer proactive protection, whereas supportive care is reactive and only offered post-infection.

Patient Experience

During the procedure, the child may feel a brief sting or discomfort from the injection. Afterward, they might experience minor pain or swelling at the injection site, which can be managed with cold compresses or acetaminophen as advised by the healthcare provider. Comfort measures include holding the child or offering a favorite toy or blanket during the injection to reduce anxiety.