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Infectious agent antigen detection by immunoassay with direct optical observation; respiratory syncytial virus

CPT4 code

Name of the Procedure:

Infectious agent antigen detection by immunoassay with direct optical observation; respiratory syncytial virus (RSV)

Summary

This procedure is a laboratory test used to detect the presence of respiratory syncytial virus (RSV) antigens in a patient’s respiratory samples. The test uses immunoassay technology combined with direct optical observation to provide a rapid diagnosis.

Purpose

This test is used to diagnose infections caused by the respiratory syncytial virus (RSV), which is particularly common and potentially severe in young children, the elderly, and individuals with weakened immune systems. The goal is to quickly identify the presence of the virus, allowing for timely treatment and management of symptoms, and to help prevent the spread of the virus to others.

Indications

  • Symptoms such as coughing, wheezing, difficulty breathing, runny nose, and fever.
  • Young children, especially infants, showing signs of bronchiolitis or pneumonia.
  • Elderly individuals or those with weakened immune systems presenting respiratory symptoms.
  • During RSV season or outbreaks when there is a high prevalence of the virus.

Preparation

  • No special preparation is typically required for the patient.
  • The healthcare provider may collect a sample from the patient’s nose or throat using a swab or wash.

Procedure Description

  1. A healthcare provider collects a respiratory sample from the patient using a nasal or throat swab.
  2. The sample is sent to a laboratory where it is mixed with special antibodies that bind to RSV antigens if present.
  3. The mixture is then analyzed using optical observation to detect any reactions indicating the presence of the virus.
  4. Results are typically available within a few hours.

Duration

The sample collection process takes only a few minutes, while lab analysis and results are usually available within a few hours to 24 hours.

Setting

The procedure is typically performed in a hospital, outpatient clinic, or specialized diagnostic laboratory.

Personnel

  • Nurse or healthcare technician for sample collection.
  • Laboratory technician or medical technologist for performing the test and analysis.

Risks and Complications

  • Common risks include minor discomfort or irritation at the site of sample collection (nose or throat).
  • Rare complications could include slight bleeding or infection at the sample site.

Benefits

  • Rapid and accurate diagnosis of RSV infection.
  • Allows for timely initiation of appropriate treatments or interventions.
  • Helps reduce the spread of the virus through early detection.

Recovery

  • No specific recovery time needed as the procedure is minimally invasive.
  • Normal activities can typically be resumed immediately after the sample is collected.

Alternatives

  • Traditional viral culture, which is more time-consuming but highly accurate.
  • Polymerase chain reaction (PCR) tests, which are also highly sensitive but can be more costly and require specialized equipment.
  • Rapid antigen tests, which are quicker but may be less sensitive than immunoassays.

Patient Experience

  • The patient may experience brief discomfort during sample collection from the nasal or throat swab.
  • Post-procedure, the patient might have mild irritation in the sample area.
  • Pain management is generally unnecessary due to the minimally invasive nature of the procedure.

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