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Infectious agent antigen detection by immunoassay with direct optical observation; adenovirus

CPT4 code

Name of the Procedure:

Infectious Agent Antigen Detection by Immunoassay with Direct Optical Observation; Adenovirus (Common Name: Adenovirus Antigen Detection Test)

Summary:

This procedure uses a specialized test to detect adenovirus antigens in the body. It employs an immunoassay technique combined with direct optical observation to identify the presence of adenovirus, which is a common cause of respiratory and gastrointestinal infections.

Purpose:

The test is designed to diagnose infections caused by adenovirus. It helps in confirming the presence of the virus, thereby aiding in appropriate treatment decisions and infection control.

Indications:

  • Symptoms such as sore throat, fever, cough, and eye redness that suggest a respiratory infection.
  • Gastrointestinal symptoms like diarrhea, vomiting, and abdominal pain that indicate a possible adenovirus infection.
  • Exposure to someone known to be infected with adenovirus.
  • Patients with weakened immune systems who are at a higher risk for severe adenovirus infections.

Preparation:

  • No specific fasting or medication adjustments are typically required.
  • Inform the healthcare provider about any medications or supplements being taken.
  • A sample collection method, such as a throat swab or stool sample, may be explained beforehand.

Procedure Description:

  1. Sample Collection: Depending on symptoms, a swab from the throat, nasal passage, or a stool sample is collected.
  2. Immunoassay: The collected sample is processed using an immunoassay. This testing method uses antibodies that bind specifically to adenovirus antigens.
  3. Direct Optical Observation: The test result is observed directly using optical equipment to confirm the presence of the antigens.
  4. Analysis: The healthcare provider interprets the results, typically available within a few hours to a day.

Duration:

The entire procedure, including sample collection and processing, generally takes a few hours. The sample collection process itself lasts only a few minutes.

Setting:

This procedure is typically performed in outpatient clinics, hospitals, or specialized diagnostic laboratories.

Personnel:

  • Medical technologists or laboratory technicians for sample processing.
  • Healthcare providers such as doctors or nurses to collect the sample and interpret results.

Risks and Complications:

  • Minor discomfort during sample collection, such as a gag reflex during a throat swab.
  • Rare risk of bleeding or infection at the sample collection site.

Benefits:

  • Rapid and accurate diagnosis of adenovirus infection.
  • Informs appropriate treatment and infection control measures.
  • Helps in preventing the spread of the virus to others.

Recovery:

  • No significant recovery time is needed after the sample collection.
  • Patients can resume normal activities immediately.
  • Follow-up may be required based on test results and overall clinical condition.

Alternatives:

  • Viral culture: More time-consuming but highly specific.
  • PCR (Polymerase Chain Reaction) testing: Highly sensitive but potentially more expensive and less widely available.
  • Symptom management without definitive diagnosis: May result in less targeted treatment.

Patient Experience:

  • Patients might experience mild discomfort during the sample collection, such as a gagging sensation or slight irritation.
  • The procedure itself should not cause significant pain.
  • Most patients will find the experience quick and relatively non-invasive.

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