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B cells, total count

CPT4 code

Name of the Procedure:

  • B cells, total count
  • Synonyms: B lymphocyte count

Summary

A B cells, total count is a blood test that measures the number of B lymphocytes (a type of white blood cell) present in the blood. B cells are crucial for the immune system as they produce antibodies and play a role in immune function.

Purpose

The test is used to:

  • Diagnose immune system disorders.
  • Monitor immune response in conditions like HIV/AIDS.
  • Evaluate patients before and after treatments that affect the immune system, such as chemotherapy or immunotherapy.

Indications

  • Recurrent infections.
  • Suspected immune deficiency disorders.
  • Monitoring immune status in patients with chronic illnesses like HIV/AIDS.
  • Pre- and post-treatment evaluation in patients undergoing immunosuppressive therapies.

Preparation

  • No fasting required.
  • Inform the doctor about any medications, as certain drugs might affect white blood cell counts.
  • A simple blood draw that usually doesn't require special diagnostic tests beforehand.

Procedure Description

  1. A blood sample is drawn from a vein, usually in the arm.
  2. The sample is sent to a laboratory where it is analyzed using flow cytometry to identify and count B cells.
  3. The results are then interpreted by a healthcare professional.

Tools:

  • Needles and syringes for blood draw.
  • Flow cytometer for cell analysis.

Anesthesia: Typically none required, though local anesthetic may be used if requested.

Duration

  • The blood draw itself takes about 5-10 minutes.
  • Laboratory analysis may take a few hours to a few days, depending on the facility.

Setting

  • Outpatient clinic
  • Hospital laboratory
  • Specialized diagnostic center

Personnel

  • Phlebotomist or nurse for the blood draw.
  • Laboratory technician for analysis.
  • Physician or hematologist for result interpretation.

Risks and Complications

  • Minor: Bruising or discomfort at the blood draw site.
  • Rare: Infection at the needle site or fainting during the blood draw.

Benefits

  • Accurate diagnosis of immune-related conditions.
  • Effective monitoring of immune function.
  • Informative for tailoring and adjusting treatments affecting the immune system.

Recovery

  • Minimal: Patients can usually resume normal activities immediately.
  • Keep the blood draw site clean and covered for a few hours.

Alternatives

  • Complete blood count (CBC) with differential: Provides a broader view of white blood cell counts but less specific for B cells.
  • Immunoglobulin levels: Measures antibodies but doesn’t directly count B cells.

Patient Experience

  • During: Slight discomfort or a pinching sensation during the blood draw.
  • After: Mild soreness at the puncture site; usually minimal pain.
  • Pain management: Over-the-counter pain relievers if necessary. Applying a cold pack can reduce swelling or bruising.

Medical Policies and Guidelines for B cells, total count

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