Name of the Procedure:

Injection, bevacizumab, 10 mg (HCPCS Code: J9035)

Summary

The procedure involves the administration of bevacizumab, a medication that's injected into the bloodstream. Bevacizumab is commonly used to slow the growth of new blood vessels and is often employed in the treatment of various cancers.

Purpose

Bevacizumab is used to treat various forms of cancer, including colorectal, lung, glioblastoma, kidney, and ovarian cancers. The goal of this injection is to inhibit the growth of blood vessels that feed tumors, thereby slowing cancer progression and potentially shrinking tumor size.

Indications

• Specific Symptoms: Persistent or recurrent cancer, tumors that are resistant to conventional therapy.
• Conditions: Metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical cancer, and recurrent ovarian cancer.
• Patient Criteria: Typically prescribed for cancer patients who have not responded to other therapies, or as part of a combination treatment.

Preparation

• Pre-procedure Instructions: No special fasting is usually required, but follow any specific instructions given by your healthcare provider.
• Diagnostic Tests: Blood tests and imaging (such as CT or MRI scans) to monitor the size and progression of tumors.

Procedure Description

1. Administering the Injection:
   • Step 1: Patient sits or lies down in a comfortable position.
   • Step 2: A nurse or doctor prepares the bevacizumab medication.
   • Step 3: The injection site is cleaned and sterilized.
   • Step 4: Bevacizumab is injected intravenously, often through an IV line in the arm.
2. Tools and Equipment: Syringe, IV line, antiseptic wipes.
3. Anesthesia/Sedation: No anesthesia is needed, but discomfort is minimal.

Duration

The procedure typically takes about 30 minutes to 1 hour, including preparation time.

Setting

The injection is usually administered in a hospital, outpatient clinic, or specialized cancer treatment center.

Personnel

• Healthcare Professionals: Oncologist, nurse, and possibly a pharmacist for medication preparation.

Risks and Complications

• Common Risks: Mild pain or discomfort at the injection site, fatigue, nausea, and hypertension.
• Rare Risks: Blood clots, gastrointestinal perforations, severe bleeding, and wound healing complications.
• Management of Complications: Close monitoring of the patient, prompt medical intervention, and supportive care treatments.

Benefits

• Expected Benefits: Slowing tumor growth, potentially shrinking tumors, alleviating cancer-related symptoms.
• Timeframe: The benefits can become noticeable within weeks to months, depending on individual response and tumor type.

Recovery

• Post-Procedure Care: Monitoring for any immediate allergic reactions or side effects.
• Recovery Time: Patients can typically return to their normal activities shortly after the procedure but should follow their doctor's specific advice.
• Restrictions/Follow-up: Regular follow-up appointments and imaging studies to monitor the treatment's effectiveness.

Alternatives

• Other Treatments: Surgery, chemotherapy, radiotherapy, other targeted therapy drugs.
• Pros and Cons: Alternative treatments may have different side effect profiles and efficacy rates. Bevacizumab is often used when other treatments have failed or are not suitable.

Patient Experience

• During the Procedure: Patients might feel a slight pinch with the IV insertion and some mild discomfort.
• After the Procedure: Potential for minimal soreness at the injection site, but normal activities can usually be resumed. Pain management can include over-the-counter pain relievers as advised by a doctor. Comfort measures include rest and hydration.

Remember to always consult with your healthcare provider for personalized advice and information about this procedure.