Name of the Procedure:

Injection, bevacizumab, 0.25 mg

Common Name(s): Avastin injection

Technical/Medical Terms: Bevacizumab administration

Summary

Bevacizumab injection is a medical procedure in which a medication called bevacizumab is administered to a patient. This drug is often used to manage conditions affecting the eyes, such as macular degeneration, by inhibiting the growth of abnormal blood vessels.

Purpose

The procedure aims to:

• Treat eye conditions like age-related macular degeneration (AMD), diabetic retinopathy, and retinal vein occlusion.
• Prevent further vision loss and, in some cases, improve vision by inhibiting abnormal blood vessel growth.

Indications

• Patients with wet age-related macular degeneration (AMD).
• Diabetic retinopathy and its complications.
• Retinal vein occlusion causing vision impairment.
• Certain types of cancer, though this guide focuses on ophthalmic use.

Preparation

• Patients might be advised to refrain from using certain medications before the procedure.
• An eye exam and possibly imaging tests to assess the condition of the retina and ensure the appropriateness of the injection.
• Informing the healthcare provider of any allergies or current medications.

Procedure Description

1. The patient is seated in an examination chair.
2. The eye is numbed using anesthetic eye drops to minimize discomfort.
3. The eye area is cleaned with an antiseptic solution.
4. A small device may be used to keep the eye open.
5. The bevacizumab is injected directly into the vitreous humor inside the eye using a fine needle.
6. After the injection, the eye may be rinsed with saline.

Duration

The procedure typically takes about 10-15 minutes.

Setting

Bevacizumab injections are usually performed in an outpatient clinic or an ophthalmologist's office.

Personnel

• An ophthalmologist or retina specialist performs the injection.
• A nurse or medical assistant may assist with preparation and post-procedure care.

Risks and Complications

• Common risks: Mild discomfort, eye redness, floaters.
• Rare risks: Infection (endophthalmitis), increased intraocular pressure, retinal detachment, or bleeding.
• Complications are managed through medication, additional procedures, or close monitoring.

Benefits

• May stabilize or improve vision in patients with specific eye conditions.
• Reduction in the growth of abnormal blood vessels, preventing further damage to the retina.
• Benefits are typically noticed within a few weeks to months.

Recovery

• Avoid strenuous activities and heavy lifting for a few days post-injection.
• Use prescribed eye drops to prevent infection and reduce inflammation.
• Regular follow-up appointments to monitor the eye condition and effectiveness of the treatment.
• Report any sudden changes in vision or severe pain to a healthcare provider immediately.

Alternatives

• Other medications: Ranibizumab (Lucentis), Aflibercept (Eylea).
• Laser therapy for certain eye conditions.
• Pros of alternatives: Some might be preferred based on individual response or specific medical conditions.
• Cons: Varying effectiveness, different side effect profiles, and frequency of treatments.

Patient Experience

• During the procedure: Mild pressure or slight discomfort in the eye.
• After the procedure: Eye may feel irritated, vision might be blurry for a few hours; eye drops will help manage discomfort.
• Pain management: Over-the-counter analgesics can be used if necessary, but significant pain should be reported to a healthcare provider.