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Subcutaneous injection of filling material (eg, collagen); over 10.0 cc

CPT4 code

Name of the Procedure:

Subcutaneous Injection of Filling Material (e.g., collagen) Over 10.0 cc


This procedure involves injecting more than 10 cubic centimeters (cc) of a filling material like collagen just beneath the skin. The aim is to restore volume and improve the appearance of specific areas.


The main goal is to address volume loss in the skin, typically caused by aging, trauma, or medical conditions. It can smooth out wrinkles, fill concave scars, and restore a youthful appearance.


  • Deep wrinkles or folds, such as nasolabial folds
  • Facial volume loss
  • Depressed scars or blemishes
  • Skin laxity
  • Non-surgical contouring of facial features


  • Follow any pre-procedure instructions from your healthcare provider.
  • Avoid blood-thinning medications like aspirin a few days prior, unless advised otherwise.
  • Arrive with a clean face, free of makeup and lotions.
  • Inform your healthcare provider about any allergies or medical conditions.

Procedure Description

  1. The area to be treated is cleansed and disinfected.
  2. A topical or local anesthetic may be applied to minimize discomfort.
  3. Using a fine needle or cannula, the filling material is injected beneath the skin in the targeted areas.
  4. The provider will massage the area to mold and distribute the filler evenly.
  5. Multiple injections may be necessary to achieve the desired result.


The entire procedure typically takes between 30 minutes to 1 hour, depending on the extent of the treatment area.


This procedure is commonly performed in outpatient settings, including clinics, dermatology offices, or cosmetic surgery centers.


  • Dermatologist or cosmetic surgeon
  • Trained nursing staff or medical assistants

Risks and Complications

  • Common: bruising, swelling, redness, tenderness at the injection sites.
  • Rare: infection, allergic reaction, granulomas (small lumps), asymmetry or uneven results, vascular complications.


  • Immediate enhancement in skin volume and contour.
  • Minimally invasive with minimal downtime.
  • Long-lasting but not permanent, allowing adjustments over time.


  • Mild swelling and bruising may occur and usually subsides within a week.
  • Avoid strenuous activities and exposure to extreme temperatures for 24-48 hours post-procedure.
  • You may be advised to avoid certain facial treatments or massages for a few weeks.
  • Follow-up appointments may be scheduled to monitor results.


  • Other dermal fillers (e.g., hyaluronic acid, poly-L-lactic acid)
  • Fat grafting or transfer
  • Surgical options like facelifts or implants
  • Skin resurfacing treatments (e.g., laser therapy, chemical peels)

Each alternative has its pros and cons, depending on the desired outcome and specific patient factors.

Patient Experience

Patients may feel slight discomfort during the injection process, similar to a pinch or sting. Post-procedure, mild tenderness and swelling are common but typically resolve quickly. Pain management may include over-the-counter analgesics and applying ice packs to reduce swelling. Overall, most patients find the procedure to be tolerable and the results rewarding.

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