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Subcutaneous injection of filling material (eg, collagen); 1.1 to 5.0 cc

CPT4 code

Name of the Procedure:

Subcutaneous Injection of Filling Material Common Name(s): Dermal Filler Injection, Collagen Injection


A subcutaneous injection of filling material involves injecting substances like collagen under the skin to restore volume, reduce wrinkles, and improve facial contours.


This procedure is used to address cosmetic concerns such as facial wrinkles, folds, and loss of volume due to aging or other factors. The goal is to achieve a smoother, more youthful appearance.


  • Deep facial lines and wrinkles
  • Thinning lips
  • Hollow cheeks or temples
  • Nasolabial folds (lines from the nose to the corners of the mouth)
  • Scars and contour irregularities The procedure is appropriate for adults in good health who have realistic expectations.


  • Avoid blood-thinning medications and supplements for at least a week before the procedure.
  • Refrain from consuming alcohol for 24 hours beforehand.
  • Inform the practitioner of any allergies or medical conditions.
  • No specific diagnostic tests are typically required.

Procedure Description

  1. The treatment area is cleaned and sometimes marked.
  2. A topical anesthetic cream may be applied to minimize discomfort.
  3. Using a fine needle, the filler material (e.g., collagen) is injected into the subcutaneous layer of the skin.
  4. The injection sites may be gently massaged to distribute the filler evenly.
  5. The procedure is repeated as necessary to achieve the desired effect.


The procedure typically takes about 30 to 60 minutes, depending on the extent of the treatment.


The procedure is performed in an outpatient setting, such as a dermatology clinic or cosmetic surgery center.


  • Dermatologist or cosmetic surgeon
  • Nurse or medical assistant

Risks and Complications

  • Common: redness, swelling, bruising, tenderness at the injection sites.
  • Rare: infection, allergic reaction, asymmetry, lumps, or migration of the filler material. Complications are generally managed with medications or corrective procedures.


  • Immediate and noticeable improvement in skin appearance.
  • Results can last from several months to over a year, depending on the type of filler used.
  • Minimal downtime and quick recovery.


  • Apply ice packs to reduce swelling and discomfort.
  • Avoid strenuous activities and excessive facial movements for 24-48 hours.
  • Follow-up appointments may be necessary for additional treatments or touch-ups.
  • Most patients return to normal activities immediately or within a few days.


  • Other fillers like hyaluronic acid, PMMA, or fat grafting.
  • Non-invasive treatments such as laser resurfacing or chemical peels.
  • Surgical options like facelifts provide longer-lasting results but with more downtime. Each alternative has its pros and cons related to duration, cost, invasiveness, and recovery time.

Patient Experience

Patients may feel slight discomfort or a pinching sensation during injections. Some tenderness or bruising can be expected post-procedure, but pain is generally minimal and manageable with over-the-counter pain relievers. Most people feel comfortable resuming their daily activities shortly after.

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