Name of the Procedure:

Hyaluronan Injection (Synvisc-One)

• Common Names: Synvisc, Synvisc-One Injection
• Technical Terms: Hyaluronan or Derivative Intra-articular Injection

Summary

Synvisc-One is an injectable treatment used to alleviate joint pain due to osteoarthritis. It involves injecting hyaluronan, a substance similar to natural joint fluid, directly into the joint to minimize pain and improve mobility.

Purpose

Medical Conditions Addressed:

• Osteoarthritis

Goals/Expected Outcomes:

• To reduce joint pain
• To improve joint function and range of motion
• To provide a lubricating and cushioning effect within the joint

Indications

Specific Symptoms/Conditions:

• Patients experiencing moderate to severe osteoarthritis pain in the knee that hasn't responded adequately to non-pharmacologic therapy and simple analgesics.

Patient Criteria:

• Patients who have not benefited sufficiently from conservative management techniques such as physical therapy and over-the-counter pain medication.

Preparation

Pre-Procedure Instructions:

• No specific fasting is required.
• Patients may be advised to continue or suspend certain medications per doctor's guidance.

Diagnostic Tests/Assessments:

• Physical examination of the affected joint
• Imaging studies like X-rays or MRI to confirm the extent of osteoarthritis

Procedure Description

Step-by-Step Explanation:

1. The patient is positioned comfortably, often sitting or lying down.
2. The skin over the affected joint is cleansed with an antiseptic solution.
3. Local anesthesia might be applied to reduce discomfort.
4. The doctor inserts a sterile needle into the joint space.
5. Synvisc-One (hyaluronan gel) is injected directly into the joint cavity.
6. The needle is removed, and a small bandage is applied to the injection site.

Tools/Equipment:

• Sterile needle and syringe
• Synvisc-One injection (hyaluronan gel)
• Antiseptic solution
• Local anesthetic (if needed)

Duration

• The injection procedure typically takes around 10 to 20 minutes.

Setting

• Performed in an outpatient clinic or doctor's office.

Personnel

• Rheumatologist or orthopedic specialist
• Nursing staff for assistance

Risks and Complications

Common Risks:

• Temporary pain and swelling at the injection site

Rare Risks:

• Infection
• Allergic reactions
• Hemarthrosis (bleeding into the joint)

Possible Complications:

• Joint stiffness
• Localized bleeding which usually resolves on its own

Benefits

Expected Benefits:

• Significant pain relief, often within a few days to weeks after the injection.
• Improved joint function and mobility.
• May delay the need for surgical interventions like knee replacement.

Recovery

Post-Procedure Care:

• Patients are usually advised to rest and avoid strenuous activity for 48 hours.
• Ice packs may be applied to reduce swelling.
• Over-the-counter pain medications can be taken for minor discomfort.

Expected Recovery Time:

• Most patients can resume normal activities within a few days.

Follow-Up:

• A follow-up visit may be scheduled to assess the effectiveness of the treatment.

Alternatives

Other Treatment Options:

• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Physical therapy
• Corticosteroid injections
• Surgery (in severe cases, such as joint replacement)

Pros and Cons of Alternatives:

• NSAIDs may not always provide sufficient pain relief and have gastrointestinal side effects.
• Physical therapy can improve function but may not significantly reduce pain.
• Corticosteroid injections can provide temporary relief but have potential long-term side effects.

Patient Experience

During the Procedure:

• Patients may feel mild discomfort or pressure during the injection process.

After the Procedure:

• Temporary discomfort or swelling at the injection site is common.
• Pain relief typically begins within a few days to weeks.

Pain Management/Comfort Measures:

• Application of ice packs to the injection site
• Mild pain relievers like acetaminophen or ibuprofen as needed