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Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

ICD10CM code

Name of the Condition

  • Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors.

Summary

This condition involves excessive bleeding caused by abnormal levels of certain proteins or antibodies that interfere with the normal blood clotting process. It is not caused by external medications like blood thinners but originates from the body's own circulatory system.

Causes

The condition can be caused by the development of autoantibodies against clotting factors, such as in cases of acquired hemophilia, or inhibitors that specifically target these proteins, leading to reduced clotting ability.

Risk Factors

  • Autoimmune disorders
  • Certain cancers
  • Infections
  • Pregnancy or postpartum period
  • Advanced age
  • Patients with a history of blood disorders

Symptoms

  • Unexplained or excessive bruising
  • Prolonged bleeding from cuts
  • Joint or muscle bleeds
  • Heavy menstrual periods
  • Gastrointestinal bleeding

Diagnosis

  • Blood tests to measure clotting factor levels
  • Tests to detect specific antibodies or inhibitors
  • Coagulation tests like prothrombin time (PT) and activated partial thromboplastin time (aPTT)

Treatment Options

  • Administration of clotting factor concentrates
  • Immunosuppressive drugs to reduce antibody production
  • Avoidance of physical activities that may lead to injury
  • Plasmapheresis to remove antibodies from the blood

Prognosis and Follow-Up

With appropriate treatment, patients can manage symptoms effectively, although some cases may require long-term therapy. Regular monitoring by healthcare providers is crucial to adjust treatment plans and prevent severe bleeding events.

Complications

  • Severe anemia due to chronic blood loss
  • Joint damage from recurrent bleeding
  • Increased risk of life-threatening hemorrhages

Lifestyle & Prevention

While specific prevention measures are not well-defined, maintaining a healthy lifestyle and managing underlying conditions such as autoimmune disorders can help reduce risk.

When to Seek Professional Help

  • Sudden, severe bleeding
  • Inability to control bleeding with standard first-aid measures
  • Signs of significant blood loss, such as weakness, shortness of breath, or dizziness

Additional Resources

  • National Hemophilia Foundation NHF
  • Hemophilia Federation of America HFA
  • American Society of Hematology ASH

Tips for Medical Coders

  • Ensure documentation specifies intrinsic causes as opposed to drug-induced anticoagulation for accurate coding.
  • Verify the presence of specific inhibitors or antibodies through lab tests noted in the patient's medical record.
  • Avoid confusion with other hemorrhagic conditions by confirming the precise cause and categorization under ICD D68.318.

Medical Policies and Guidelines for Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

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