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Peripheral T-cell lymphoma, not classified, extranodal and solid organ sites
ICD10CM code
Name of the Condition
- Peripheral T-cell lymphoma, not elsewhere classified, extranodal and solid organ sites (ICD-10 Code: C84.49)
Summary
- Peripheral T-cell lymphoma, not elsewhere classified, is a rare, aggressive form of non-Hodgkin lymphoma. It originates from mature T-cells and primarily affects organs other than the lymph nodes, such as the liver, spleen, or skin.
Causes
- The exact cause is unclear, but genetic mutations, immune system deficiencies, and viral infections like the Epstein-Barr virus (EBV) may contribute to its development.
Risk Factors
- Risk factors include older age, male gender, a history of autoimmune diseases, exposure to certain chemicals, and infections with viruses like HTLV-1 or EBV.
Symptoms
- Symptoms may include swelling or lumps, fatigue, fever, night sweats, unexplained weight loss, and organ-related symptoms depending on where the lymphoma has spread.
Diagnosis
- Diagnosis typically involves a combination of physical examination, imaging tests (e.g., CT or PET scans), blood tests, and biopsy of affected tissues for histological analysis.
Treatment Options
- Treatment may involve chemotherapy, radiation therapy, or a combination of both. Stem cell transplant might be considered in certain cases. Treatments aim to eliminate cancer cells and manage symptoms.
Prognosis and Follow-Up
- The prognosis varies based on factors like the stage at diagnosis and response to treatment. Regular follow-ups are crucial to monitor for recurrence and manage potential side effects of treatment.
Complications
- Potential complications include infection, organ failure, and treatment-related side effects, such as fatigue and susceptibility to further health issues.
Lifestyle & Prevention
- While specific prevention strategies are limited due to the unclear causes, maintaining a healthy lifestyle with a balanced diet and regular exercise can support overall health and immune function.
When to Seek Professional Help
- Seek medical attention for persistent and unexplained symptoms such as lumps, extreme fatigue, or significant weight loss to rule out serious conditions like lymphoma.
Additional Resources
Tips for Medical Coders
- Verify the site of the lymphoma to ensure correct coding; extranodal and solid organ sites should be distinguished from lymph node involvement.
- Avoid errors by confirming that the classification is "not elsewhere classified" under peripheral T-cell lymphoma.