C81.98 Hodgkin lymphoma, unspecified, lymph nodes of multiple sites

ICD-10-CM Diagnosis Code C81.98: Hodgkin lymphoma, unspecified, lymph nodes of multiple sites

ICD-10-CM code C81.98 identifies Hodgkin lymphoma, unspecified, affecting the lymph nodes of multiple sites. The terminology record is active and classifies this concept as a neoplastic process. It exists as a narrower concept under the parent code C81.9, which denotes Hodgkin lymphoma, unspecified. This code is distinct from C81.99, which applies to extranodal and solid organ sites. 1 5

Plain-language overview

Code C81.98 carries the official label Hodgkin lymphoma, unspecified, lymph nodes of multiple sites, and its terminology record is currently active for the ICD-10-CM 2026 version. 1

What this code represents

The concept represented by C81.98 is classified under the semantic type of neoplastic process within the ICD-10-CM terminology, distinguishing it as a tumor-related diagnosis. 1

Code C81.98 is a narrower concept under the parent code C81.9, which is designated for Hodgkin lymphoma, unspecified, establishing a direct hierarchical relationship in the coding system. 1

Coding details

Code C81.98 for Hodgkin lymphoma of multiple lymph node sites is listed alongside C81.99, which is designated for Hodgkin lymphoma of extranodal and solid organ sites. 5

A Medicare billing and coding article includes C81.98 within guidelines that reference Hodgkin lymphoma across various lymph node regions, including the head, face, neck, and multiple sites. 3

Documentation considerations

The official terminology record for C81.98 specifies the neoplastic process involves the lymph nodes of multiple sites, distinguishing it from codes for localized regions or solid organs. 1 5

Coverage and utilization context

Code C81.98 appears in a Medicare article concerning allogeneic hematopoietic cell transplantation for primary refractory or relapsed Hodgkin's lymphoma with B-cell or T-cell origin. 5

What the sources add

While a clinical summary details the unpredictable nature and extranodal spread of non-Hodgkin lymphoma, the C81.98 terminology record specifically categorizes Hodgkin lymphoma of multiple lymph node sites. 1 2

Multiple official sources confirm the exact label for C81.98, with a Medicare billing article and a terminology explorer both listing Hodgkin lymphoma, unspecified, lymph nodes of multiple sites. 4 5

Sources

1. ICD-10-CM C81.98 terminology record — National Cancer Institute Enterprise Vocabulary Services; accessed 2026-07-27.
2. Bookshelf — ncbi.nlm.nih.gov; accessed 2026-07-27.
3. MCD Search — cms.gov; accessed 2026-07-27.
4. EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-27.
5. Article - Billing and Coding: Allogeneic Hematopoietic Cell Transplantation for Primary Refractory or Relapsed Hodgkin's and Non-Hodgkin's Lymphoma with B-cell or T-cell Origin (A59259) — cms.gov; accessed 2026-07-27.