Injection, Belinostat, 10 mg (J9032) Procedure Guide

Name of the Procedure:

• Common Name(s): Belinostat Injection
• Technical Term: Injection, belinostat, 10 mg
• HCPCS Code: J9032

Summary

Belinostat injection is a medical procedure where belinostat, an anticancer medication, is administered intravenously to treat certain types of cancers. The drug works by inhibiting the growth of cancer cells.

Purpose

• Medical Conditions Addressed:
  • Peripheral T-cell lymphoma (PTCL)
  • Used in patients who have already undergone other treatments without success
• Goals/Expected Outcomes:
  • To slow down or stop the progression of cancer
  • Achieve remission in cancer symptoms
  • Improve quality of life for patients

Indications

• Specific Symptoms or Conditions:
  • Diagnosed peripheral T-cell lymphoma
  • Refractory or relapsed PTCL after other treatment methods
• Patient Criteria/Factors:
  • Patients who are deemed suitable by an oncologist
  • Patients who haven't responded to other treatments

Preparation

• Pre-Procedure Instructions:
  • Fasting is not typically required
  • Adjustments might be needed for ongoing medications as advised by the oncologist
• Diagnostic Tests/Assessments:
  • Blood tests to determine liver and kidney function
  • Complete blood count (CBC)
  • Imaging studies to evaluate the extent of the cancer

Procedure Description

• Step-by-Step Explanation:
  1. Patient is positioned comfortably, usually in a sitting or reclining chair.
  2. An intravenous (IV) line is placed into a vein, typically in the arm.
  3. Belinostat is administered through the IV over a prescribed infusion time.
• Tools/Equipment:
  • Intravenous (IV) catheter
  • Infusion pump or drip apparatus
  • Belinostat medication
• Anesthesia/Sedation:
  • Not typically required as the patient remains awake

Duration

• Time Required:
  • The entire infusion process can take approximately 30 minutes to a couple of hours, depending on the patient's condition and response.

Setting

• Location:
  • Typically performed in a hospital oncology unit or an outpatient cancer treatment clinic.

Personnel

• Healthcare Professionals Involved:
  • Oncologist
  • Oncology nurse
  • Pharmacist (for preparing the medication)

Risks and Complications

• Common Risks:
  • Nausea and vomiting
  • Fatigue
  • Fever
• Rare Risks:
  • Severe allergic reactions
  • Liver toxicity
  • Low blood cell counts leading to increased infection risk
• Management of Complications:
  • Regular monitoring with blood tests
  • Immediate medical attention for severe reactions

Benefits

• Expected Benefits:
  • Reduction in tumor size
  • Alleviation of symptoms
  • Potential remission of cancer
• Realization Timeline:
  • Benefits may be noticed within weeks to months; individual response times vary

Recovery

• Post-Procedure Care:
  • Hydration encouragement
  • Ongoing monitoring for side effects
  • Follow-up appointments as scheduled
• Expected Recovery Time:
  • Varies depending on individual response and side effects experienced
  • Ongoing treatment may be required

Alternatives

• Other Treatment Options:
  • Alternative chemotherapy drugs
  • Radiation therapy
  • Stem cell transplant
• Pros and Cons:
  • Alternatives vary in effectiveness and side effects
  • Doctor’s recommendation is based on the patient’s specific condition and overall health

Patient Experience

• During the Procedure:
  • Mild discomfort from IV placement
  • Generally painless infusion process
• After the Procedure:
  • Possible tiredness or mild side effects
  • Pain management involves standard medications like acetaminophen (Tylenol)
  • Comfort measures include rest, hydration, and nutritional support

Patients should discuss their specific medical conditions and concerns with their healthcare provider to understand the best course of action.