Name of the Procedure:

Injection, von Willebrand factor complex (human), Wilate, 1 i.u. vwf:rco (HCPCS Code J7183)

Summary

This procedure involves administrating a medication known as Wilate, which contains a human-derived complex of von Willebrand factor. It's used to help manage and treat bleeding disorders associated with von Willebrand disease.

Purpose

Von Willebrand disease is a genetic disorder caused by missing or defective von Willebrand factor, a clotting protein. The goal of this procedure is to replace the deficient protein to help the blood clot properly, thereby preventing or treating bleeding episodes.

Indications

• Patients with von Willebrand disease who experience frequent and severe bleeding.
• Individuals who need surgery or dental procedures and are at risk of excessive bleeding.
• Patients with a deficiency of von Willebrand factor documented by blood tests.

Preparation

• Patients may need to undergo blood tests to assess clotting levels.
• Fasting is generally not required.
• Discuss any medications with your doctor, as some may need to be adjusted.

Procedure Description

1. The healthcare provider prepares the Wilate injection by reconstituting the powder in a vial with sterile water.
2. The patient’s skin is cleaned at the injection site, usually in the arm.
3. Wilate is injected intravenously over a few minutes.
   • Tools: Syringe, sterile vial of Wilate, sterile water.
   • Sedation is typically not required.

Duration

The entire process typically takes about 15-30 minutes, including preparation and administration.

Setting

This procedure is commonly performed in a hospital, outpatient clinic, or at home under medical supervision.

Personnel

• Healthcare provider (nurse or doctor) to administer the injection.
• Pharmacist to prepare the Wilate dosage.
• Occasionally, a hematologist might be involved for specialized cases.

Risks and Complications

• Common risks: Mild discomfort at the injection site, headache, nausea.
• Rare risks: Allergic reactions, rash, fever, increased heart rate, dizziness.
• Management: Monitoring during and after the injection, use of antihistamines or epinephrine for severe reactions.

Benefits

• Effective control or prevention of bleeding episodes.
• Improved quality of life and reduced need for emergency medical interventions.
• Benefits can be visible within hours to a day after administration.

Recovery

• Resume normal activities shortly after the procedure.
• Follow-up blood tests may be scheduled to monitor clotting levels.
• Avoid strenuous activities for 24 hours if advised by your doctor.

Alternatives

• Desmopressin (DDAVP) for mild cases.
• Blood or plasma transfusions.
• Each alternative has its own risks and benefits, but Wilate directly replaces the missing protein, often making it a preferred choice for severe cases.

Patient Experience

• Mild pain or discomfort at the injection site is possible.
• Minimal downtime with little to no lasting discomfort.
• Any pain is typically manageable with over-the-counter pain relievers if necessary.

Remember to always discuss potential risks, benefits, and alternatives with your healthcare provider to make an informed decision tailored to your specific medical needs.