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Hepatitis Be antibody (HBeAb)

CPT4 code

Name of the Procedure:

Hepatitis Be Antibody (HBeAb) (Common names: HBeAb test, Hepatitis B envelope antibody test)

Summary

The Hepatitis Be Antibody (HBeAb) test is a blood test used to detect antibodies against the Hepatitis B virus (HBV). This antibody is produced in response to the 'e' antigen (HBeAg) of the HBV. The presence of HBeAb typically indicates the reduced replicative activity of the virus and a lower risk of transmission.

Purpose

The HBeAb test is primarily used to:

  • Monitor the progression of Hepatitis B infection.
  • Evaluate the effectiveness of antiviral treatment.
  • Assess the infectiousness of a person with Hepatitis B.

Indications

The HBeAb test may be indicated for patients who;

  • Are known carriers of Hepatitis B.
  • Present chronic Hepatitis B symptoms or complications.
  • Are undergoing treatment for Hepatitis B.
  • Require assessment of their viral load and disease status.

Preparation

  • No special fasting or preparation is required for the HBeAb test.
  • It’s recommended to inform your healthcare provider about any medications or current health conditions.

Procedure Description

  1. Blood Sample Collection:

    • A healthcare professional will clean the site (arm or hand) with an antiseptic.
    • A tourniquet is applied to the upper arm to fill the veins with blood.
    • A needle is inserted into the vein to draw blood into a vial or syringe.
    • The sample is labeled and sent to a laboratory for analysis.
  2. Laboratory Analysis:

    • The blood sample is tested for the presence of HBeAb using immunoassays.

Duration

  • The blood draw typically takes about 10 minutes.
  • Laboratory results are usually available within a few days to a week.

Setting

  • The blood sample is collected in a healthcare setting such as a hospital, outpatient clinic, or diagnostic lab.

Personnel

  • The procedure is performed by a phlebotomist or a trained nurse.
  • A laboratory technician conducts the analysis.

Risks and Complications

  • Common risks include slight pain or bruising at the needle site.
  • Rare complications might involve infection or dizziness.

Benefits

  • Helps in determining the patient's stage of Hepatitis B infection.
  • Guides the healthcare provider in making informed decisions about treatment plans.
  • Reduces the risk of spreading the virus through accurate monitoring.

Recovery

  • Minimal recovery is required; patients can usually resume normal activities immediately.
  • Instructions may include applying pressure at the puncture site to minimize bleeding.

Alternatives

  • Hepatitis B Virus DNA Test (HBV DNA): Measures the amount of viral DNA to determine viral load but is more complex and expensive.
  • Hepatitis B Surface Antigen (HBsAg) Test: Identifies active infection but cannot assess the replication status comprehensively.

Patient Experience

  • Mild discomfort at the site of blood withdrawal.
  • Any pain or bruising typically subsides within a few days.
  • Staying hydrated and avoiding strenuous activities on the same arm used for blood draw may promote comfort.

This comprehensive information aids in understanding the purpose, execution, and implications of the HBeAb test, ensuring well-informed patients and providers.

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