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ICD-10-CM T36.4X5: Adverse effect of tetracyclines
ICD-10-CM code T36.4X5 represents the adverse effect of tetracyclines, classified under the parent concept of poisoning, adverse effect, and underdosing of tetracyclines. The terminology record is active for the 2026 version and carries the semantic type of injury or poisoning. This code is distinct from accidental or assault-related tetracycline poisoning codes. 1 3
Plain-language overview
The official terminology record for T36.4X5 assigns the preferred name of adverse effect of tetracyclines and classifies this concept with the semantic type of injury or poisoning. 1
What this code represents
The official display label for T36.4X5 is adverse effect of tetracyclines, and the concept is active within the 2026 ICD-10-CM version. The terminology record assigns this code the semantic type of injury or poisoning. 1 4
Coding details
T36.4X5 has no narrower child concepts and is linked to the parent concept T36.4X, which covers poisoning, adverse effects, and underdosing of tetracyclines. Sibling codes include accidental and assault-related tetracycline poisoning. 1 3
The terminology hierarchy lists T36.4X5 as a concept within the broader T36.4X category, distinguishing it from sibling codes that specify accidental or assault-related tetracycline poisoning. 3
Documentation considerations
Clinical literature indicates that gastrointestinal disturbances and dermatological side effects are documented adverse effects of tetracyclines, providing context for the clinical scenarios associated with this code. 2
Clinical context
Research indicates gastrointestinal disturbances are the most common adverse effects of tetracyclines, while dermatological side effects like photosensitivity and rash are frequently associated with doxycycline and minocycline. 2
What the sources add
The terminology source establishes the official code hierarchy and active status, whereas the clinical research source provides operational context regarding the specific physical reactions patients experience during tetracycline use. 1 2
Coverage and utilization context
The code T36.4X5 appears in an electronic medical reference application, confirming its inclusion in searchable diagnostic tools available for clinical and coding reference. 5
Sources
- ICD-10-CM T36.4X5 terminology record — National Cancer Institute Enterprise Vocabulary Services; accessed 2026-07-27.
- Long-Term Safety Profiles of Macrolides and Tetracyclines: A Systematic Review and Meta-Analysis — pmc.ncbi.nlm.nih.gov; accessed 2026-07-27.
- EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-27.
- EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-27.
- T36.4X5 - Adverse effect of tetracyclines | ICD-10-CM — unboundmedicine.com; accessed 2026-07-27.
T36.4X5 policy automation walkthrough
Walk through the policies, prior authorization requirements, and workflow automation opportunities connected to this code.