Name of the Condition

• Systemic Inflammatory Response Syndrome (SIRS) of Non-Infectious Origin with Acute Organ Dysfunction
• ICD-10 Code: R65.11

Summary

Systemic Inflammatory Response Syndrome (SIRS) of non-infectious origin with acute organ dysfunction is a critical medical condition where the body's systemic inflammation leads to dysfunction of one or more organs, not caused by an infection. It can arise from various causes, necessitating urgent medical intervention.

Causes

• Trauma, such as severe injury or surgery.
• Burns.
• Pancreatitis.
• Autoimmune disorders like lupus.
• Hemorrhage or severe blood loss.
• Other severe stressors on the body.

Risk Factors

• Severe injury or recent surgical procedures.
• Existing chronic health conditions.
• Autoimmune diseases.
• Exposure to extreme physical stress or injury.

Symptoms

• Fever or hypothermia.
• Rapid heartbeat and breathing.
• Changes in mental status, such as confusion or lethargy.
• Decreased urine output.
• Sudden drop in blood pressure.

Diagnosis

• Clinical evaluation based on SIRS criteria, which includes abnormal body temperature, heart rate, respiratory rate, and abnormal white blood cell count.
• Organ function tests (e.g., liver function tests, kidney function tests).
• Imaging studies to assess organ damage.
• Blood tests to rule out infection.

Treatment Options

• Medications: Anti-inflammatory drugs or corticosteroids to reduce inflammation.
• Supportive care: Intravenous fluids, oxygen therapy, or mechanical ventilation if necessary.
• Surgery: May be required to address underlying causes like trauma or organ damage.
• These treatments help stabilize the patient and support failing organs while addressing the underlying cause.

Prognosis and Follow-Up

• The prognosis depends on the underlying cause and the timeliness of treatment.
• Regular monitoring of organ function is essential during recovery.
• Follow-ups typically involve managing chronic conditions and preventing recurrence.

Complications

• Multi-organ failure.
• Prolonged hospitalization.
• Increased risk for infections.
• Permanent organ damage if untreated.

Lifestyle & Prevention

• Managing chronic health conditions more effectively.
• Maintaining a balanced diet and regular exercise.
• Early and adequate management of injuries and conditions to prevent progression to SIRS.

When to Seek Professional Help

• Rapid or labored breathing.
• Extreme fatigue or confusion.
• Very high or low body temperature.
• Any signs of organ dysfunction like decreased urine output.

Additional Resources

• American College of Chest Physicians and Society of Critical Care Medicine
• MedlinePlus
• National Institute of General Medical Sciences

Tips for Medical Coders

• Ensure accurate documentation of the absence of infection as this differentiates R65.11 from related infectious codes.
• Confirm documentation of acute organ dysfunction as it impacts coding accuracy.
• Avoid common errors such as coding SIRS without specified organ dysfunction or incorrectly attributing the condition to infections.