C84.Z4 Other mature T/NK-cell lymphomas, lymph nodes of axilla and upper limb

ICD10CM code

#### Name of the Condition
- Other mature T/NK-cell lymphomas, lymph nodes of axilla and upper limb (**ICD Code: C84.Z4**).

#### Summary
- This condition involves a group of uncommon lymphomas that originate from mature T-cells or natural killer (NK) cells, primarily affecting the lymph nodes in the axilla (armpit) and upper limb areas.

#### Causes
- The exact cause is often unknown but may include genetic mutations and environmental factors. Viral infections such as the Epstein-Barr Virus (EBV) or Human T-cell leukemia virus (HTLV) can sometimes be associated with these lymphomas.

#### Risk Factors
- Factors that may increase the risk include age (typically middle-aged and older adults), male gender, certain ethnic backgrounds, having a compromised immune system, and a history of certain viral infections.

#### Symptoms
- Common symptoms include swelling or lumps in the axilla or upper limbs, fever, night sweats, unexplained weight loss, and fatigue.

#### Diagnosis
- Diagnosis typically involves a combination of physical examination, imaging tests (like CT or PET scans), blood tests, and biopsy of the lymph nodes to analyze cell types.

#### Treatment Options
- Treatment can vary based on the lymphoma type and stage, including chemotherapy, radiation therapy, targeted therapy, and sometimes stem cell transplant. Each treatment aims to reduce or eliminate cancer cells, manage symptoms, and prevent progression.

#### Prognosis and Follow-Up
- Prognosis depends on the lymphoma subtype and response to treatment. Regular follow-up is important for monitoring treatment response and managing potential relapses.

#### Complications
- Untreated, it can lead to progression and spread to other organs. Complications from therapy can include infections, anemia, or secondary malignancies.

#### Lifestyle & Prevention
- While prevention is challenging due to unknown causes, maintaining a healthy immune system, managing viral infections promptly, and regular medical check-ups might be beneficial.

#### When to Seek Professional Help
- Seek medical advice if you notice persistent swelling of lymph nodes, unexplained weight loss, recurrent fever, or other systemic symptoms suggestive of lymphoma.

#### Additional Resources
- Visit the American Cancer Society or Leukemia & Lymphoma Society for more information and support resources.

#### Tips for Medical Coders
- Ensure the correct anatomical site is noted as the axilla and upper limb. Be cautious of the specific subtype classification and use ICD code C84.Z4 for accurate coding.
- Avoid confusing this condition with other lymphomas affecting different lymph nodes or regions.

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