Name of the Procedure:

Injection, pemetrexed (Pemfexy), 10 mg

• Common name: Pemfexy Injection
• Technical/medical term: Injection, pemetrexed

Summary

The pemetrexed (Pemfexy) injection is a chemotherapy treatment administered to patients diagnosed with certain types of cancer. This medicine is given through an injection and is aimed at slowing or stopping the growth of cancer cells.

Purpose

Pemetrexed injections are used to treat specific types of cancer, such as mesothelioma and non-small cell lung cancer (NSCLC). The goal is to inhibit cancer cell growth, reduce tumor size, and improve symptoms associated with these conditions.

Indications

• Malignant pleural mesothelioma
• Non-small cell lung cancer
• Patients who have cancer that has spread despite other treatments

Preparation

• Patients may need to fast for a few hours before the procedure.
• Blood tests and other diagnostic evaluations are typically performed to ensure the patient is suitable for treatment.
• Pre-medications, including folic acid and vitamin B12, are often required to minimize side effects.

Procedure Description

1. The injection is given intravenously (into a vein).
2. A healthcare professional will insert a needle into the vein to administer the medication.
3. Tools include a syringe or infusion bag, intravenous line, and necessary protective equipment.
4. No anesthesia is required, but mild sedation may be administered if needed.

Duration

The administration of a pemetrexed injection typically takes about 10 to 15 minutes.

Setting

This procedure is usually performed in an outpatient clinic, hospital, or infusion center.

Personnel

• Oncologist: Supervises and orders the treatment.
• Nurse: Administers the injection and monitors the patient for side effects.
• Pharmacist: Prepares the medication.

Risks and Complications

• Common risks: Nausea, fatigue, low blood cell counts, liver enzyme changes, and rash.
• Rare complications: Severe allergic reactions, kidney problems, and lung inflammation.
• Management involves supportive care and monitoring by the oncology team.

Benefits

• The primary benefit is the potential to slow or stop the progression of cancer.
• Symptom improvement, including pain relief and better breathing.
• Benefits may be observed within weeks of starting treatment.

Recovery

• Patients can typically return home shortly after the injection.
• Mild side effects may last for a few hours to days.
• Regular follow-up appointments are crucial to monitor response and manage any side effects.
• Avoid heavy lifting and strenuous activities for a short period as advised by the healthcare provider.

Alternatives

• Other chemotherapy drugs
• Radiation therapy
• Surgery
• Targeted therapy and immunotherapy
• Pros and cons vary; alternatives may be less effective or have different side effect profiles.

Patient Experience

• During the procedure, patients might feel a mild sting at the injection site.
• Side effects like nausea and fatigue can be managed with medications and rest.
• Most patients resume normal activities within a day, but should follow specific instructions given by their healthcare provider.