Name of the Procedure:

Injection, doxercalciferol, 1 mcg
Common Name: Doxercalciferol Injection
Technical Term: Vitamin D2 Analog Injection

Summary

This procedure involves the administration of doxercalciferol, a synthetic form of vitamin D2, via injection. Doxercalciferol helps regulate calcium and phosphorus levels in the body, and it may be used to treat conditions associated with low levels of these minerals.

Purpose

Doxercalciferol injections are primarily used to manage secondary hyperparathyroidism in patients undergoing chronic kidney dialysis. The goal of the procedure is to help maintain balanced levels of calcium and phosphorus in the bloodstream, thereby preventing bone disease and other complications associated with kidney failure.

Indications

• Secondary hyperparathyroidism in patients with chronic kidney disease (CKD) on dialysis.
• Elevated levels of parathyroid hormone (PTH).
• Abnormally low serum calcium and phosphorus levels despite dietary or oral supplementation.

Preparation

• Patients may need to undergo blood tests to measure levels of calcium, phosphorus, and parathyroid hormone (PTH) prior to the injection.
• Doctors may advise adjustments in dietary habits or oral supplements based on the results of these tests.
• No fasting or significant preparation is typically required.

Procedure Description

1. The healthcare provider draws the appropriate dose of doxercalciferol (1 mcg) into a sterile syringe.
2. The injection site, usually the upper arm or thigh, is cleaned with an antiseptic to prevent infection.
3. The needle is then inserted into the muscle, and the medication is injected.
4. The site of injection is bandaged.

Tools and Equipment:

• Sterile syringe and needle
• Antiseptic wipes
• Bandage

Anesthesia:

• Typically, no anesthesia or sedation is needed.

Duration

The entire process from preparation to injection usually takes about 10-15 minutes.

Setting

This procedure is typically performed in an outpatient clinic, dialysis center, or hospital.

Personnel

• Doctor or Physician Assistant (PA)
• Registered Nurse (RN) or Licensed Practical Nurse (LPN)

Risks and Complications

Common Risks:

• Pain or discomfort at the injection site
• Mild bruising or swelling

Rare Risks:

• Allergic reaction to the medication
• Hypercalcemia (high calcium levels)
• Hypophosphatemia (low phosphorus levels)

Possible Complications:

• Management includes monitoring blood levels and adjusting dosages as necessary.

Benefits

• Improved regulation of calcium and phosphorus levels.
• Reduction in symptoms associated with secondary hyperparathyroidism.
• Potentially reduced risk of complications like bone disease and cardiovascular issues.

Recovery

Post-Procedure Care:

• Monitoring for immediate adverse reactions at the injection site.
• Regular blood tests to monitor calcium, phosphorus, and PTH levels.

Expected Recovery Time:

• No downtime; usual activities can typically be resumed immediately.
• Regular follow-up appointments to ensure efficacy and adjust dosing as needed.

Alternatives

• Oral vitamin D analogs or other medications, such as calcitriol. Pros and Cons:
• Oral medications are easier to administer but may be less effective for some patients on dialysis.
• Intravenous options may be an alternative when injection sites become problematic.

Patient Experience

• The injection might cause brief discomfort similar to any routine shot.
• Patients might feel mild soreness at the injection site for a short period. Pain Management and Comfort Measures:
• Over-the-counter pain relievers may be used to alleviate any minor discomfort.
• Applying an ice pack to the injection site can reduce swelling and soreness.

This document provides an overview of the Injection, doxercalciferol, 1 mcg (J1270) procedure, highlighting its purpose, indications, preparation, and other key aspects to help patients understand the treatment's role in managing their condition. All medical procedures should be discussed thoroughly with a healthcare professional to ensure it aligns with the patient's specific health needs.