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Collagen dressing, sterile, size 16 sq. in. or less, each

HCPCS code

Collagen Dressing, Sterile, Size 16 sq. in. or Less, Each (A6021)

Name of the Procedure:

  • Common Name(s): Collagen Dressing, Wound Dressing
  • Technical/Medical Term: Collagen Dressing Application


A collagen dressing is a sterile bandage infused with collagen, which helps in the healing of wounds. It is used to cover and protect wounds, promoting faster and more efficient healing.


Collagen dressings are used to manage and treat wounds, ulcers, and certain conditions where skin integrity is compromised. The goals are to enhance the healing process, protect the wound from infection, and manage wound exudate.


  • Chronic wounds such as pressure sores, diabetic ulcers, and vascular ulcers
  • Surgical wounds that have reopened
  • Partial-thickness burns
  • Venous or arterial ulcers
  • Donor sites and grafts
  • Traumatic wounds


  • Pre-procedure Instructions: The wound area should be cleaned and disinfected. Patients do not usually need to fast or adjust medications unless specified by their healthcare provider.
  • No specific diagnostic tests are required, but a healthcare provider may assess the wound type, size, depth, and infection status to determine the appropriateness of the collagen dressing.

Procedure Description

  1. Cleanse the wound with saline or an appropriate wound cleanser.
  2. Pat the wound dry with sterile gauze.
  3. Open the sterile collagen dressing package.
  4. Cut the dressing to fit the wound size, ensuring coverage of the entire wound bed.
  5. Apply the collagen dressing directly onto the wound.
  6. Secure with a secondary dressing or bandage to keep it in place.
    • Tools/Equipment Used: Sterile scissors, saline or wound cleanser, sterile gloves, secondary dressing.
    • Anesthesia or Sedation: Typically not required.


The application process usually takes about 15-30 minutes, depending on the wound's complexity.


Collagen dressings can be applied in various settings including hospitals, outpatient clinics, nursing homes, or at home by a healthcare provider.


  • Nurses
  • Wound care specialists
  • Physicians (in some cases)

Risks and Complications

  • Possible allergic reactions to the collagen or other components
  • Infection if the dressing is not properly applied or changed regularly
  • Skin irritation or maceration from improper use
  • Rare risk of delayed wound healing


  • Accelerated wound healing
  • Reduction of infection risk
  • Effective absorption of wound exudate
  • Maintains a moist wound environment, which is conducive to healing


  • Post-Procedure Care: Regular dressing changes as instructed by a healthcare provider. Keep the area clean and dry between changes.
  • Expected Recovery Time: Varies depending on wound severity; regular monitoring by healthcare providers is required.
  • Restrictions/Follow-Up Appointments: Patients may need to avoid certain activities that could disturb the wound. Regular follow-up appointments to assess healing progress.


  • Hydrocolloid dressings: Offer a moist environment but do not have collagen's specific benefits.
  • Foam dressings: Provide more absorption but lack collagen's biological properties.
  • Traditional gauze: Inexpensive but less effective in providing optimal healing conditions.

Pros of Alternatives:

  • Hydrocolloid and foam dressings can be easier to use for some patients.
  • Gauze is widely available and inexpensive.

Cons of Alternatives:

  • May not promote healing as effectively as collagen dressings.
  • Higher risk of wound desiccation or infection compared to collagen dressings.

Patient Experience

  • During the Procedure: Typically painless, may feel a sensation of coolness when the dressing is applied.
  • After the Procedure: Patients may experience no significant discomfort; any minor discomfort can often be managed with standard over-the-counter pain relief if needed. Regular dressing changes are required and involve minimal discomfort.

Proper wound care and adherence to healthcare provider instructions are essential for optimal healing outcomes.

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