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Chlorhexidine containing antiseptic, 1 ml

HCPCS code

Name of the Procedure:

Chlorhexidine Containing Antiseptic, 1 ml
Common Name: Chlorhexidine Prep
Technical Term: Chlorhexidine Gluconate Antiseptic Application


Chlorhexidine antiseptic is a procedure involving the application of a 1 ml solution of chlorhexidine gluconate to the skin to reduce bacteria and prevent infections.


Chlorhexidine antiseptic is used to disinfect skin areas before surgical procedures, injections, or catheter insertions. Its goal is to decrease the risk of infection by eliminating harmful bacteria on the skin.


  • Pre-surgical skin disinfection
  • Before catheter insertion
  • Prior to injections
  • For wound cleansing or minor cuts
  • Instances where a sterile field is critical


  • Clean the area with soap and water if visibly soiled.
  • Allow the skin to dry thoroughly.
  • No fasting or special medication adjustments are typically required.

Procedure Description

  1. Clean hands and wear sterile gloves.
  2. Open the chlorhexidine antiseptic package.
  3. Apply the 1 ml antiseptic solution to a sterile applicator or directly to the skin.
  4. Cleanse the area with a back-and-forth motion for at least 30 seconds.
  5. Allow the area to air dry completely; do not rinse.


The application process typically takes around 1-2 minutes.


This procedure is usually performed in a clinical setting such as a hospital, outpatient clinic, or surgical center.


  • Nurses
  • Medical assistants
  • Physicians or surgeons (if applied just before surgery)

Risks and Complications

  • Mild skin irritation or redness
  • Allergic reaction (rare)
  • Contact dermatitis (uncommon)


  • Significant reduction in the risk of infection
  • Immediate and lasting antibacterial protection on the skin


  • Minimal to no recovery time required
  • No specific post-procedure care needed unless advised otherwise
  • Instructions may include keeping the area clean and dry


  • Povidone-iodine antiseptic
  • Alcohol-based antiseptic solutions
  • Soap and water, though less effective for surgical-level sterility

Pros of chlorhexidine:

  • Superior lasting effect
  • Greater reduction in bacterial load


  • Possible skin irritation compared to other agents

Patient Experience

  • Typically, patients feel a cooling or drying sensation during application.
  • Minimal discomfort or pain is expected.
  • Immediate resumption of regular activities in most cases. Pain management is generally unnecessary.

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