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Antibody; Treponema pallidum

CPT4 code

Name of the Procedure:

Antibody; Treponema pallidum test (also known as Syphilis Serology Test, Syphilis Antibody Test)

Summary

The Treponema pallidum antibody test is a blood test used to detect antibodies produced in response to the bacteria that cause syphilis, a sexually transmitted infection (STI).

Purpose

The test is used to diagnose an active or past infection with Treponema pallidum, the bacteria responsible for syphilis. It helps in identifying if a person has been infected with the bacteria, ensuring timely treatment and preventing complications.

Indications

  • Unexplained sore or rash, particularly on the genitals, mouth, or anus.
  • Routine screening during pregnancy.
  • Unprotected sexual contact or a new sexual partner.
  • Symptoms of secondary syphilis like fever, sore throat, and swollen lymph nodes.
  • Screening for individuals diagnosed with another STI.
  • Follow-up testing after syphilis treatment.

Preparation

  • No special preparation is needed.
  • Inform your healthcare provider of any medications or supplements you are taking.

Procedure Description

  1. A healthcare professional will apply antiseptic to cleanse the area, typically on the arm.
  2. A tourniquet is applied above the site to fill the veins with blood.
  3. A sterile needle is inserted into the vein to draw a blood sample.
  4. The collected blood is sent to a laboratory for analysis to detect antibodies against Treponema pallidum.
    • No anesthesia or sedation is required.

Duration

The blood draw typically takes about 5-10 minutes.

Setting

This procedure is performed in a clinical laboratory, a doctor's office, or an outpatient clinic.

Personnel

  • The primary healthcare provider or a trained phlebotomist conducts the blood draw.
  • Laboratory technicians analyze the blood sample.

Risks and Complications

  • Minor discomfort or pain at the needle insertion site.
  • Slight risk of bruising or hematoma.
  • Rare chances of infection at the puncture site.

Benefits

  • Early and accurate diagnosis of syphilis.
  • Enables prompt treatment to prevent severe complications, such as neurological damage.
  • Helps in reducing the spread of syphilis by identifying and treating infected individuals.

Recovery

  • Post-procedure care involves applying pressure and a bandage over the puncture site.
  • Patients can resume normal activities immediately after the blood draw.
  • Follow-up may involve reviewing the test results and, if positive, discussing treatment options with a healthcare provider.

Alternatives

  • Rapid Plasma Reagin (RPR) or Venereal Disease Research Laboratory (VDRL) tests: screen for syphilis through different markers.
  • Darkfield microscopy: direct detection of the bacteria in lesion samples.
  • Each alternative has varying sensitivities and specificities, depending on the stage of infection and clinical context.

Patient Experience

  • Mild discomfort or a brief sting during the needle insertion.
  • Minor soreness or bruising might occur at the puncture site.
  • Most patients tolerate the procedure well without significant distress.
  • Pain management usually is not necessary, but some patients may find comfort in deep breathing or distraction techniques during the blood draw.

Medical Policies and Guidelines for Antibody; Treponema pallidum

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