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Antibody; cytomegalovirus (CMV), IgM

CPT4 code

Name of the Procedure:

Antibody; Cytomegalovirus (CMV), IgM
Common name: CMV IgM Test


The CMV IgM test is a blood test used to detect the presence of IgM antibodies against cytomegalovirus, indicating a recent or current CMV infection. It helps physicians diagnose CMV-related illnesses and monitor immune responses.


The CMV IgM test addresses potential CMV infections, which can be particularly serious in pregnant women, newborns, and immunocompromised individuals. The goal is to confirm a CMV infection, allowing for appropriate treatment and management to mitigate complications.


  • Symptoms such as fever, fatigue, swollen glands, or other signs of infection.
  • Pregnant women suspected of CMV infection.
  • Newborns showing signs of congenital CMV infection.
  • Immunocompromised patients (e.g., organ transplant recipients, HIV/AIDS patients) displaying symptoms of CMV.


  • No specific preparation such as fasting is required for the test.
  • Patients should inform their healthcare provider about all medications and supplements they are taking.
  • Discuss any recent infections or underlying health conditions with the healthcare provider.

Procedure Description

  1. Blood Sample Collection: A healthcare professional typically draws a blood sample from a vein in the arm using a sterile needle and collection tube.
  2. Laboratory Analysis: The blood sample is sent to a laboratory, where it is analyzed for the presence of CMV IgM antibodies using specialized assays and equipment.
  3. Results Reporting: Results are reported to the healthcare provider, who will interpret the findings in the context of the patient's clinical symptoms and history.


The blood draw itself takes only a few minutes. Laboratory analysis may take a few days to a week, depending on the testing facility.


The blood sample is usually collected in a hospital, outpatient clinic, or doctor’s office. The analysis is performed in a specialized diagnostic laboratory.


  • Phlebotomist or nurse for blood sample collection.
  • Laboratory technicians or medical technologists for sample analysis.
  • Doctor or healthcare provider to interpret results and provide follow-up care.

Risks and Complications

  • Minor pain or discomfort at the needle insertion site.
  • Possible bruising or slight bleeding.
  • Rare risks include infection or feeling lightheaded.


  • Accurate diagnosis of CMV infection, allowing for timely and appropriate treatment.
  • Helps prevent complications, especially in high-risk populations such as pregnant women and immunocompromised patients.
  • Provides crucial information for monitoring the infection status and immune response.


  • Minimal recovery required.
  • Patients can usually resume normal activities immediately after the blood draw.
  • Follow any specific aftercare instructions provided by the healthcare provider.


  • CMV IgG test to determine past exposure and immunity.
  • CMV PCR test to detect viral DNA, confirming active infection.
  • Clinical evaluation and other laboratory tests to assess overall health and related conditions.

Patient Experience

  • During: Minor discomfort during blood sample collection; a slight pinch or sting when the needle is inserted.
  • After: Some patients may experience mild bruising or tenderness at the puncture site, which usually resolves quickly.
  • Pain management: If necessary, over-the-counter pain relievers like acetaminophen can be used for minor discomfort.

Medical Policies and Guidelines for Antibody; cytomegalovirus (CMV), IgM

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