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Fibrinogen; antigen

CPT4 code

Name of the Procedure:

Fibrinogen; Antigen Test Common names: Fibrinogen antigen test, Quantitative fibrinogen test, Fibrinogen level test.


A Fibrinogen antigen test is a blood test that measures the amount of fibrinogen, a vital protein in blood clotting, in your bloodstream. This test helps assess your body’s ability to form blood clots.


This test addresses conditions related to blood clotting disorders. The primary goals are to diagnose bleeding disorders, monitor levels of fibrinogen in patients with liver disease, disseminated intravascular coagulation (DIC), or those chronic conditions that might affect clotting factors.


  • Unexplained or excessive bleeding.
  • Symptoms of a clotting disorder (e.g., frequent nosebleeds, excessive bruising).
  • Monitoring in cases of chronic diseases affecting liver function.
  • Evaluation of patients with suspected disseminated intravascular coagulation (DIC).


  • Fasting might be required for a few hours before the test.
  • Inform your healthcare provider about any medications, as some might need to be adjusted before the procedure.
  • No specific diagnostic tests are required beforehand, although a complete blood count (CBC) might be done concurrently.

Procedure Description

  1. Blood Sample Collection:

    • A healthcare professional will clean the area, usually the inside of your elbow or back of your hand, with an antiseptic.
    • A tourniquet is applied to your upper arm to fill the vein with blood.
    • Using a sterilized needle, the healthcare professional will draw blood into a tube.
  2. Laboratory Analysis:

    • The sample is sent to a lab, where fibrinogen levels are measured using immunoassays.

No anesthesia or sedation is involved, as this is a minimally invasive procedure.


The blood draw itself typically takes 5-10 minutes. Lab analysis can take a few hours to a few days depending on the facility.


Performed in a hospital, outpatient clinic, diagnostic laboratory, or a doctor's office.


Involves a phlebotomist or a nurse to draw the blood and lab technicians to analyze the sample.

Risks and Complications

  • Common: Minor bruising or discomfort at the puncture site.
  • Rare: Infection at the puncture site, excessive bleeding, fainting, or hematoma formation.
  • Management: Applying pressure to the puncture site can minimize bruising and bleeding; follow up with your healthcare provider if you experience persistent pain or signs of infection.


  • Helps diagnose bleeding and clotting disorders.
  • Assists in monitoring the effectiveness of treatment for certain chronic conditions and clotting disorders.
  • Results can typically be realized within a few days.


  • Minimal recovery time; patients can usually resume normal activities immediately.
  • Follow any specific instructions provided by your healthcare provider.
  • Schedule any follow-up appointments if necessary, particularly if abnormal results are found.


  • Prothrombin Time (PT) and Activated Partial Thromboplastin Time (aPTT): These tests also evaluate clotting function but focus on different aspects of the clotting process.
  • Factor Assays: Specific measurements of other clotting factors that might be indicated based on initial test results.
  • Pros/Cons: These alternatives may offer more comprehensive insights but also require additional blood draws and specialized testing.

Patient Experience

  • Mild discomfort from the needle prick during blood draw.
  • Most patients report minimal pain and no significant side effects.
  • Any post-procedure discomfort can be managed with over-the-counter pain relief and simple home care for the puncture site.

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