Ketosteroids, 17- (17-KS); total
CPT4 code
Name of the Procedure:
Ketosteroids, 17- (17-KS); total
Common name: 17-Ketosteroid Test
Technical/medical term: 17-Ketosteroids, Total Urine Test
Summary
The 17-Ketosteroid Test is a diagnostic urine test that measures the levels of 17-ketosteroids in the body. These are the byproducts of the breakdown of steroid hormones, such as androgens and corticosteroids.
Purpose
The test is used to evaluate the function of the adrenal glands and gonads (testes in men and ovaries in women). It helps in diagnosing disorders related to abnormal hormone production.
Indications
- Symptoms of adrenal gland disorders such as Cushing's syndrome or Addison's disease.
- Signs of androgen excess or deficiency.
- Monitoring the effectiveness of treatment for adrenal gland disorders.
Preparation
- Patients may be asked to stop certain medications that can affect test results.
- Pregnant women may need special instructions as hormone levels can be elevated during pregnancy.
- A 24-hour urine collection is required, so patients should be prepared to collect all urine over a full day.
Procedure Description
- The patient collects all urine for 24 hours in a special container.
- The collected urine is kept cold, either refrigerated or placed in a container with ice.
- After 24 hours, the collected sample is returned to the lab for analysis.
- The lab measures the total amount of 17-ketosteroids in the urine sample.
Duration
The urine collection takes 24 hours. Lab analysis may take several days.
Setting
The sample collection is done at home by the patient. The analysis is performed in a laboratory.
Personnel
- The patient or their caregiver collects the urine.
- Lab technicians and medical technologists perform the analysis.
Risks and Complications
- There are minimal risks since this is a non-invasive test.
- Potential for inaccurate results if the urine collection is not done correctly.
Benefits
- Provides valuable information on adrenal and gonadal function.
- Helps diagnose hormonal imbalances and monitor treatment efficacy.
Recovery
No recovery time is needed since it is a non-invasive test, and there are no post-procedure restrictions.
Alternatives
- Serum testosterone or cortisol levels.
- Adrenal imaging studies (e.g., CT or MRI scans).
- Different types of hormone panels that may include additional or different biomarkers.
Patient Experience
During and after the procedure, the patient experiences no discomfort other than the inconvenience of collecting urine over 24 hours. Pain management is not necessary.