30 Day Change Notice Form

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30 Day Change Notice

Indications

(10001) Is Dyanavel XR Tab covered? 
(10002) Is prior authorization required for Dyanavel XR Tab? 
(20001) Is Brixadi covered? 
(20002) Is prior authorization required for Brixadi? 
(30001) Is Lokelma covered? 

YesNoN/A
YesNoN/A
YesNoN/A

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Effective Date

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Last Reviewed

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Original Document

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Ohio Department of Medicaid 30 Day Change Notice Effective Date: April 1, 2024

THERAPEUTIC CLASS NO PA REQUIRED PREFERRED
Central Nervous System (CNS) Agents: Attention Deficit Hyperactivity Disorder Agents Dyanavel XR Tab
Central Nervous System (CNS) Agents: Medication Assisted Treatment of Opioid Addiction Brixadi
Hyperkalemia Agents: Potassium Binders Lokelma
Otic Agents: Antibacterial and Antibacterial/Steroid Combinations Ciprofloxacin/Dexamethasone
Respiratory Agents: Inhaled Agents Arnuity Ellipta
Fluticasone Propionate
Qvar
THERAPEUTIC CLASS CLINICAL CRITERIA REQUIRED PREFERRED
Immunomodulator Agents: Systemic Inflammatory Disease Amjevita
Respiratory Agents: Pulmonary Fibrosis Ofev
THERAPEUTIC CLASS PA REQUIRED NON-PREFERRED
Endocrine Agents: Growth Hormone Ngenla
Hyperkalemia Agents: Potassium Binders Sodium Polystyrene Sulfonate Veltassa
Immunomodulator Agents: Systemic Inflammatory Disease Adalimumab-aacf
Ophthalmic Agents: Glaucoma Agents Iyuzeh
Respiratory Agents: Inhaled Agents Airsupra
Breyna
Respiratory Agents: Pulmonary Fibrosis Pirfenidone

Central Nervous System (CNS) Agents: Attention Deficit Hyperactivity Disorder Agents Central Nervous System (CNS) Agents: Medication Assisted Treatment of Opioid Addiction Central Nervous System (CNS) Agents: Narcolepsy Infectious Disease Agents: Antivirals – Hepatitis C Agents

Date of Notice: 03/1/2024

Ohio Department of Medicaid 30 Day Change Notice Effective Date: April 1, 2024

THERAPEUTIC CLASS SUMMARY OF CHANGE
Central Nervous System (CNS) Agents: Attention Deficit Hyperactivity Disorder Agents AR – Adderall, Dexedrine, & Zenzedi IR: a PA is required for patients younger than 3 years
AR – Adderall XR, Atomoxetine, Cotempla XR-ODT, Daytrana, Dexedrine ER, Dexmethylphenidate, Methylphenidate IR & ER, & Xelstrym: a PA is required for patients younger than 6 years
AR – Dextroamphetamine Solution & Dyanavel XR: a PA is required for patients 12 years and older
AR – Methylphenidate solution/suspension/chewable tab: a PA is required for patients younger than 6 years and 12 years and older
Central Nervous System (CNS) Agents: Medication Assisted Treatment of Opioid Addiction ADDITIONAL INFORMATION
Vivitrol, and Sublocade, and Brixadi may not be billed by the pharmacy if it is not dispensed directly to the patient. If not administered by the pharmacist, the drug must be released only to the administering provider or administering provider’s staff, following all regulations for a Prescription Pick-Up Station as described by the Ohio Board of Pharmacy.
Central Nervous System (CNS) Agents: Narcolepsy AR – Methylphenidate: a PA is required for patients younger than 6 years
Infectious Disease Agents: Antivirals – Hepatitis C Agents The following documentation must be submitted with initial request for consideration of approval:
☐ Active HCV infection verified by viral load within 180 days HCV RNA: __ million IU/mL Date __
☐ HCV Genotype verified by lab (must also indicate genotype): ☐ 1a ☐ 1b ☐ 2 ☐ 3 ☐ 4 ☐ 5 ☐ 6
Note: HCV genotype is not required if all of the follow apply:
• Patient is treatment naïve AND
• No evidence of cirrhosis AND
• Requesting simplified treatment regimen (either or a, b)
a. Mayvret 100/40 mg: three (3) tablets daily for 8 weeks
b. Sofosbuvir/velpatasvir 400/100 mg, one tablet daily for 12 weeks
Hepatitis fibrosis stage __ Date __
Method(s) used:
☐ Individuals scheduled to receive an HCVNS3 protease inhibitor (i.e. grazoprevir, voxilaprevir, glecaprevir) should be assessed for a history of decompensated liver disease and liver disease severity using the Child-Turcotte-Pugh (CTP) score if cirrhosis is determined to be likely present (as evidenced by clinical findings, radiology, Metavir fibrosis score of F4, pathology findings, or other laboratory markers (FibroTest/FibroSure/Fib-4 index).
☐ Prescriber has discussed the importance of adherence to treatment plan, office visits, lab monitoring, imaging, procedures, and to talking about requested regimen as prescribed.
☐ Individual does not have limited life expectancy (less than 12 months) due to non-liver-related comorbid conditions.

Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia A, von Willebrand Disease, and Factor XIII Deficiency Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia B Hyperkalemia Agents: Potassium Binders Respiratory Agents: Pulmonary Fibrosis

Date of Notice: 03/1/2024

Ohio Department of Medicaid 30 Day Change Notice Effective Date: April 1, 2024

THERAPEUTIC CLASS SUMMARY OF CHANGE
Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia A, von Willebrand Disease, and Factor XIII Deficiency* Split the original class (Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia Factor*) into separate categories. No changes to drug placement or changes in clinical criteria.
Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia B* Split the original class (Blood Formation, Coagulation, and Thrombosis Agents: Hemophilia Factor*) into separate categories. No changes to drug placement or changes in clinical criteria.
Hyperkalemia Agents: Potassium Binders LENGTH OF AUTHORIZATIONS: 365 Days
ALL AUTHORIZATIONS: Must be prescribed in accordance with FDA approved labeling
NON-PREFERRED CRITERIA:
• Must provide documentation of medical necessity beyond convenience for why the patient cannot be changed to a preferred drug (i.e., allergies, drug-drug interactions, contraindications, or intolerances) OR
• Must have had an inadequate clinical response of at least 30 days with at least one preferred drug
○ For non-preferred extended-release formulations: must provide documentation of an inadequate clinical response with its immediate release formulation (if available)
○ For non-preferred brand names that have preferred generics: must provide documentation of an inadequate clinical response or allergy to two or more generic labelers (if available)
SUBSEQUENT AUTHORIZATION CRITERIA:
Must provide documentation of patient’s clinical response to treatment and ongoing safety monitoring
Respiratory Agents: Pulmonary Fibrosis LENGTH OF AUTHORIZATIONS: 365 Days
ALL AUTHORIZATIONS: Must be prescribed in accordance with FDA approved labeling
CLINICAL PA CRITERIA:
• Must be prescribed by or in consultation with a pulmonologist
NON-PREFERRED CRITERIA:
• Must provide documentation of medical necessity beyond convenience for why the patient cannot be changed to a preferred

drug (i.e., allergies, drug-drug interactions, contraindications, or intolerances) OR |

| | ○ For any nonsolid oral dosage formulation: must provide documentation of medical necessity for why patient cannot be changed to a solid oral dosage formulation |

| | • Must have had an inadequate clinical response of at least 30 days with at least one preferred drug |

| | ○ For non-preferred extended-release formulations: must provide documentation of an inadequate clinical response with its immediate release formulation (if available) |

| | ○ For non-preferred brand names that have preferred generics: must provide documentation of an inadequate clinical response or allergy to two or more generic labelers (if available) |

| | SUBSEQUENT AUTHORIZATION CRITERIA: |

| | • Must provide documentation of patient’s clinical response to treatment and ongoing safety |

Date of Notice: 03/1/2024

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