P58.9 Neonatal jaundice due to excessive hemolysis, unspecified

ICD-10-CM P58.9: Neonatal jaundice due to excessive hemolysis, unspecified

ICD-10-CM code P58.9 identifies neonatal jaundice resulting from excessive hemolysis when the specific cause is not specified. The code is an active, billable diagnosis classified under parent category P58. General clinical sources describe neonatal jaundice as unconjugated hyperbilirubinemia from hepatic immaturity or blood cell incompatibility, but do not define this exact code. 1 2 3

Plain-language overview

Neonatal jaundice involves unconjugated hyperbilirubinemia in newborns, often resulting from hepatic immaturity and low enzyme activity during the second through fifth days of life. 2

Blood group incompatibilities, such as ABO or Rh factors, may lead to hyperbilirubinemia and consequently cause neonatal jaundice in affected newborns. 2

What this code represents

Code P58.9 represents the pathologic function of neonatal jaundice due to excessive hemolysis, unspecified, and holds an active record status within the ICD-10-CM version 2026 terminology. 1

The P58.9 diagnosis code is a billable code utilized for specifying neonatal jaundice due to excessive hemolysis when the underlying condition remains unspecified. 3

Coding details

Within the ICD-10-CM hierarchy, P58.9 is a narrower concept under the parent concept P58, which covers neonatal jaundice due to other excessive hemolysis. 1

The code P58.9 falls under chapter 16 of the ICD-10-CM coding system, encompassing the range between categories P50 and P61 based on its structural URL path. 3

Documentation considerations

Clinical evaluation of unconjugated hyperbilirubinemia includes considering chronic liver diseases, infections, thyrotoxicosis, and drugs that interfere with bilirubin uptake or conjugation. 2

What the sources add

While the terminology record establishes the official code hierarchy and active status, the billing reference adds operational context by confirming the code is billable. 1 3

The clinical reference adds that mild neonatal jaundice resolves without treatment within weeks, but severe instances may require an exchange transfusion to dilute bilirubin and maternal antibody levels. 2

Sources

1. ICD-10-CM P58.9 terminology record — National Cancer Institute Enterprise Vocabulary Services; accessed 2026-07-27.
2. Bookshelf — ncbi.nlm.nih.gov; accessed 2026-07-27.
3. Codigo. The #1 Billing Agency for Medical Practices — codigo.care; accessed 2026-07-27.