H47.333 Pseudopapilledema of optic disc, bilateral

ICD-10-CM H47.333: Pseudopapilledema of optic disc, bilateral

ICD-10-CM code H47.333 represents pseudopapilledema of the optic disc, bilateral. Pseudopapilledema describes an elevated optic nerve appearance that can be challenging to distinguish from true disc edema based on fundoscopic appearance alone. Various optic disc abnormalities can create this appearance, and differentiating it from true papilledema may involve ancillary testing like intravenous fluorescein angiography. 1 3 4

Plain-language overview

Pseudopapilledema is a condition where the optic disc has an elevated appearance, and a variety of optic disc abnormalities can create this appearance including optic disc drusen, congenital disc anomalies, and myelinated nerve fibers. 1

It can be challenging to distinguish pseudopapilledema from true papilledema or disc edema based on the fundoscopic appearance of the optic nerve alone. 1

What this code represents

The ICD-10-CM code H47.333 is explicitly designated for pseudopapilledema of the optic disc when the condition is bilateral. 3 4

Within the ICD-10-CM code tree, H47.333 falls under the category of other disorders of the optic disc, and distinct codes exist for the right eye, left eye, and unspecified eye. 5

Documentation considerations

The gold standard test for the diagnosis of true optic disc edema or papilledema is intravenous fluorescein angiography, which will show leakage from the nerve if true disc edema is present. 1

Pseudopapilledema will only show late staining of the nerve on intravenous fluorescein angiography testing, and optical coherence tomography cannot reliably distinguish disc edema from pseudopapilledema. 1

What the sources add

A deep learning algorithm using near-infrared reflectance images demonstrated high diagnostic performance in distinguishing optic disc edema from pseudopapilledema and may serve as a clinical decision support tool. 2

While clinical literature from the National Center for Biotechnology Information details the differential diagnosis and testing for pseudopapilledema, the Centers for Medicare and Medicaid Services article lists H47.333 within a billing and coding context for ophthalmic diagnostic imaging. 1 3

Sources

1. Bookshelf — ncbi.nlm.nih.gov; accessed 2026-07-25.
2. Differentiation of optic disc edema and pseudopapilledema with deep learning on near-infrared reflectance images — pmc.ncbi.nlm.nih.gov; accessed 2026-07-25.
3. Article - Billing and Coding: Scanning Computerized Ophthalmic Diagnostic Imaging (SCODI) (A57804) — cms.gov; accessed 2026-07-25.
4. EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-25.
5. ICD-10-CM 2024 | H47.3 - Other disorders of optic disc — unboundmedicine.com; accessed 2026-07-25.