H35.123 Retinopathy of prematurity, stage 1, bilateral

ICD-10-CM Code H35.123: Retinopathy of prematurity, stage 1, bilateral

ICD-10-CM code H35.123 identifies retinopathy of prematurity, stage 1, bilateral. This active diagnosis concept is classified under the parent category H35.12 and represents a disease or syndrome. It is distinct from codes for the right eye, left eye, or unspecified eye involvement. 1 3

Plain-language overview

Retinopathy of prematurity is a disease of retinal vascular and capillary proliferation affecting premature infants undergoing oxygen therapy, and stage 1 is characterized by a demarcation line. 2

What this code represents

Code H35.123 represents the diagnosis of retinopathy of prematurity, stage 1, bilateral, and is an active terminology concept with the semantic type of disease or syndrome. 1

Coding details

The code H35.123 is a specific concept nested under the parent code H35.12 for stage 1 retinopathy of prematurity, distinguishing bilateral involvement from right eye, left eye, and unspecified eye codes. 1 3

Documentation considerations

Clinical documentation for this condition is classified by disease stage, zone of retinal involvement, and the presence or absence of plus disease, which is a marker of severe vascular activity. 2

What the sources add

While terminology records define the exact code and label for bilateral stage 1 disease, clinical literature provides context that screening guidelines are based on gestational age and birth weight. 1 2

Multiple terminology sources and code directories consistently list H35.123 as retinopathy of prematurity, stage 1, bilateral, alongside related codes for unspecified eye involvement. 3 5

Clinical context

The clinical classification of retinopathy of prematurity stages the disease from mild, defined as stage 1, to severe, defined as stage 5 total retinal detachment, based on the International Classification of Retinopathy of Prematurity. 2

Coverage and utilization context

The code H35.123 appears in code directories and maps to other terminologies like SNOMEDCT_US, but the supplied sources do not establish specific payer coverage criteria or reimbursement rules for this diagnosis. 4 5

Sources

1. ICD-10-CM H35.123 terminology record — National Cancer Institute Enterprise Vocabulary Services; accessed 2026-07-27.
2. Bookshelf — ncbi.nlm.nih.gov; accessed 2026-07-27.
3. ICD-10 | Retinopathy of prematurity, stage 1 (H35.12) — cdek.pharmacy.purdue.edu; accessed 2026-07-27.
4. EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-27.
5. MedicareDrop — medicaredrop.com; accessed 2026-07-27.