Name of the Condition

• Estrogen Excess (ICD Code: E28.0)
• Also known as hyperestrogenism.

Summary

• Estrogen excess is a condition characterized by an abnormally high level of estrogen in the body. It can affect both men and women, leading to a variety of health issues depending on the severity and duration of the hormonal imbalance.

Causes

• Estrogen excess can be caused by factors such as hormone replacement therapy, obesity, chronic stress, use of certain medications, and estrogen-producing tumors. In women, it may also be linked to polycystic ovary syndrome (PCOS) or menstrual cycle irregularities.

Risk Factors

• Common risk factors include obesity, sedentary lifestyle, high-fat diets, excessive alcohol consumption, and certain genetic conditions. Women with a history of irregular periods or hormone-related conditions are also at increased risk.

Symptoms

• Symptoms may include weight gain, bloating, mood swings, fatigue, breast tenderness, and menstrual irregularities. In men, symptoms can include infertility and gynecomastia (breast tissue development).

Diagnosis

• Diagnosis is typically made through a combination of a detailed medical history, physical examination, and blood tests measuring estrogen levels. Additional tests might be conducted to exclude other conditions.

Treatment Options

• Treatments focus on addressing the underlying cause and may include lifestyle modifications, medications to reduce estrogen levels, or surgery in the case of tumors. Hormonal therapy may be used to restore balance.

Prognosis and Follow-Up

• With appropriate treatment, symptoms usually improve and the prognosis is generally good. Regular follow-up appointments are important to monitor hormone levels and adjust treatment as necessary.

Complications

• If left untreated, estrogen excess can lead to complications such as increased risk of breast cancer, endometrial cancer, thromboembolic events, and infertility.

Lifestyle & Prevention

• Maintaining a healthy weight, engaging in regular physical activity, and limiting alcohol intake can help manage estrogen levels. A balanced diet rich in fiber and low in refined sugars and fats is advisable.

When to Seek Professional Help

• Seek medical attention if experiencing persistent symptoms such as unexplained weight gain, severe mood swings, or significant menstrual changes. Men noticing breast tissue development should also consult a healthcare provider.

Additional Resources

• The Hormone Health Network: Offers information on hormone-related conditions.
• Endocrine Society: Provides resources for understanding and managing hormonal imbalances.

Tips for Medical Coders

• Ensure accurate coding by verifying the presence of supporting clinical documentation for estrogen excess.
• Avoid confusion with related or similar conditions by confirming the specific diagnosis of hyperestrogenism.