D49.5 Neoplasm of unspecified behavior of other genitourinary organs

ICD-10-CM D49.5: Neoplasm of unspecified behavior of other genitourinary organs

ICD-10-CM code D49.5 designates a neoplasm of unspecified behavior affecting other genitourinary organs. The terminology record classifies this concept as a neoplastic process under the parent category D49. Historical urology coding updates note D49.5 was slated for deletion and replacement by more specific kidney and organ codes, though current terminology records still list it as active. 1 2 6

Plain-language overview

Code D49.5 identifies a neoplastic process in other genitourinary organs, and the official terminology record assigns this exact diagnosis code the preferred name of Neoplasm of unspecified behavior of other genitourinary organs. 1 6

What this code represents

The official display label for D49.5 is Neoplasm of unspecified behavior of other genitourinary organs, and the concept is semantically typed as a neoplastic process. 1

In the ICD-10-CM hierarchy, D49.5 is a child concept of D49, which is the category for neoplasms of unspecified behavior, and it currently has no narrower subordinate concepts. 1

Coding details

To increase coding specificity, a urology update detailed that D49.5 would be deleted and replaced by specific kidney laterality codes and a new D49.59 code for other genitourinary organs. 2

The replacement codes intended to add specificity include D49.511 for the right kidney, D49.512 for the left kidney, and D49.519 for an unspecified kidney. 2

Documentation considerations

A urology coding update states that to increase specificity, D49.5 will be deleted and replaced with three more specific codes that add the specific organ and laterality to this section. 2

Coverage and utilization context

A Medicare billing article for molecular diagnostic tests includes D49.59, the code for neoplasm of unspecified behavior of other genitourinary organ, within a list of related diagnosis codes. 4

What the sources add

While the standard terminology record lists D49.5 as an active code with no narrower concepts, the urology coding update establishes a historical plan to delete D49.5 in favor of more specific organ and laterality codes. 1 2

A research web resource lists the exact display label for D49.5 alongside more specific concepts for right kidney, left kidney, unspecified kidney, and other genitourinary organ neoplasms of unspecified behavior. 3

Sources

1. ICD-10-CM D49.5 terminology record — National Cancer Institute Enterprise Vocabulary Services; accessed 2026-07-27.
2. ICD-10 Changes for October 1, 2016 of Interest to Urologists — pmc.ncbi.nlm.nih.gov; accessed 2026-07-27.
3. Phecode 195.1 · ExPRSweb — csg.sph.umich.edu; accessed 2026-07-27.
4. Article - Billing and Coding: MolDX: bioTheranostics Cancer TYPE ID® Update (A54388) — cms.gov; accessed 2026-07-27.
5. Article - Billing and Coding: Removal of Benign Skin Lesions (A57113) — cms.gov; accessed 2026-07-27.
6. EVS Explore — evsexplore.semantics.cancer.gov; accessed 2026-07-27.