C83.33 Diffuse large B-cell lymphoma, intra-abdominal lymph nodes

ICD10CM code

#### Name of the Condition
- Diffuse Large B-cell Lymphoma, Intra-abdominal Lymph Nodes (ICD code: C83.33)
- Often abbreviated as DLBCL

#### Summary
- Diffuse large B-cell lymphoma (DLBCL) is a type of non-Hodgkin lymphoma that originates in the lymphatic system. It involves fast-growing tumors in the lymph nodes, most commonly in the intra-abdominal region, impacting organs such as the spleen and liver.

#### Causes
- The exact cause of DLBCL is unknown, but it is believed to result from genetic mutations affecting B-cells, possibly influenced by previous infections or immune system dysfunctions.

#### Risk Factors
- Advanced age
- Family history of lymphoma
- Infections with certain viruses (e.g., HIV, Epstein-Barr Virus)
- Immunosuppressive treatment or conditions
- Exposure to chemicals like pesticides

#### Symptoms
- Swollen or painful abdominal lymph nodes
- Unexplained weight loss
- Fever
- Night sweats
- Fatigue
- Abdominal discomfort or fullness

#### Diagnosis
- Physical examination
- Imaging tests (CT scan, PET scan)
- Biopsy of affected lymph nodes
- Blood tests to assess overall health and organ function

#### Treatment Options
- Chemotherapy: Often the primary treatment, which targets and kills rapidly dividing cancer cells.
- Immunotherapy: Drugs like rituximab help the immune system recognize and attack cancer cells.
- Radiation therapy: Used occasionally to target specific areas.
- Stem cell transplant: Considered in certain cases to restore healthy blood cells after intensive treatment.

#### Prognosis and Follow-Up
- Prognosis can vary; many patients respond well to treatment with a possibility of remission.
- Follow-up care is crucial to monitor for recurrence and manage any side effects of treatment.

#### Complications
- Untreated DLBCL can spread to other parts of the body, leading to serious complications.
- Treatment side effects, including fatigue, infections, or secondary cancers

#### Lifestyle & Prevention
- Maintaining a healthy immune system through a balanced diet, regular exercise, and avoiding excess alcohol/tobacco.
- While specific prevention methods are not established, reducing risk factors like exposure to certain infections or chemicals may help.

#### When to Seek Professional Help
- Persistent abdominal pain or noticeable swelling
- Fever or night sweats that are unexplained
- Sudden or significant weight loss

#### Additional Resources
- American Cancer Society: [cancer.org](https://www.cancer.org/)
- Lymphoma Research Foundation: [lymphoma.org](https://www.lymphoma.org/)
- Leukemia & Lymphoma Society: [lls.org](https://www.lls.org/)

#### Tips for Medical Coders
- Ensure accurate assignment of ICD code C83.33 specifically for intra-abdominal lymph node involvement.
- Be cautious of differentiating between similar non-Hodgkin lymphoma types to avoid miscoding.

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