Name of the Procedure:

• Common Name: Cisplatin Injection
• Technical Term: Injection, cisplatin, powder or solution, 10 mg (J9060)

Summary:

Cisplatin injection is a chemotherapy treatment where a solution or powder of the drug cisplatin, measured in 10 mg doses, is administered to patients. This procedure is part of cancer therapy, aimed to slow or stop the growth of cancer cells.

Purpose:

• Medical Conditions Addressed: Treats various types of cancer, including lung, ovarian, bladder, and testicular cancer.
• Goals: To reduce tumor size, inhibit cancer cell proliferation, and manage cancer-related symptoms. Success is measured by reducing tumor markers and improving patient survival rates.

Indications:

• Specific Symptoms/Conditions: Presence of malignant tumors sensitive to cisplatin.
• Patient Criteria: Suitable for individuals diagnosed with cancers where cisplatin has proven effective. Typically used after careful evaluation by an oncologist.

Preparation:

• Pre-Procedure Instructions: May require fasting for several hours before administration. Hydrate adequately as directed by the healthcare provider.
• Diagnostic Tests: Blood tests to assess kidney function and overall health. Imaging scans to evaluate tumor size and location might be necessary.

Procedure Description:

1. Step-by-Step Explanation:
   1. Patient checks in and is seated or reclined in an infusion chair.
   2. An intravenous (IV) line is inserted into a vein.
   3. Cisplatin, mixed as either powder or solution, is prepared in the pharmacy.
   4. The medication is administered through the IV over a specified duration (usually 1 to 4 hours).
2. Tools/Equipment: IV catheter, infusion pump, sterile solution of cisplatin.
3. Anesthesia/Sedation: Typically no anesthesia or sedation is required, but anti-nausea medications may be given beforehand.

Duration:

• The infusion generally takes between 1 to 4 hours.

Setting:

• Location: Administered in a hospital, outpatient clinic, or specialized infusion center.

Personnel:

• Healthcare Professionals Involved: Oncologist, chemotherapy-certified nurse, and pharmacy staff.

Risks and Complications:

• Common Risks: Nausea, vomiting, kidney function impairment, low blood cell counts, and neuropathy.
• Rare Risks: Severe allergic reactions, hearing loss, and electrolyte imbalances. Management includes immediate intervention by healthcare providers, supportive medications, and close monitoring.

Benefits:

• Expected Benefits: Reduction in tumor size, slowing of cancer progression, and symptomatic relief. Benefits often become noticeable after several cycles of treatment.

Recovery:

• Post-Procedure Care: Hydration is essential to protect kidney function. Regular blood tests to monitor cell counts and kidney function.
• Recovery Time: Recovery varies; common side effects like fatigue may last for several days. Restrictions developed based on individual response.
• Follow-Up: Typically involves regular oncologist visits and MRI/CT scans to monitor progress.

Alternatives:

• Other Treatments: Surgery, radiation therapy, alternative chemotherapy drugs, targeted therapy, and immunotherapy.
• Pros and Cons: Alternatives are considered based on cancer type, stage, and patient health, and they may have different efficacy and side effect profiles.

Patient Experience:

• During and After Procedure: Patients may experience mild discomfort during the IV insertion, nausea, or fatigue. Pain management includes prescribed anti-nausea medications and, if necessary, pain relievers. Comfort measures may include warm blankets, hydration, and a calm environment.

By understanding these facets of cisplatin injection, patients and caregivers can better prepare for and navigate the treatment process.