Anti-phosphatidylserine (phospholipid) antibody
CPT4 code
Name of the Procedure:
Anti-phosphatidylserine (phospholipid) antibody test
Summary
The anti-phosphatidylserine antibody test is a blood test used to detect the presence of antibodies against phosphatidylserine, a type of phospholipid found in cell membranes. This test helps diagnose conditions related to abnormal blood clotting.
Purpose
This test is used primarily to investigate unexplained blood clotting disorders, recurrent miscarriages, or autoimmune conditions such as antiphospholipid syndrome (APS). The goal is to identify the presence of these specific antibodies to better understand and manage clotting risks.
Indications
- Unexplained venous or arterial thrombosis
- Recurrent miscarriages
- Livedo reticularis (a purplish skin discoloration)
- Autoimmune disease diagnosis, particularly systemic lupus erythematosus (SLE)
Preparation
- Generally, no special preparation is required.
- Inform your doctor about any medications you are taking as some may affect the test results.
Procedure Description
- A phlebotomist will clean the injection site on your arm.
- A tourniquet is applied above the elbow.
- A needle is inserted to draw a blood sample into a vial.
The blood sample is then sent to a laboratory for analysis.
No anesthesia or sedation is typically needed for a blood draw.
Duration
The blood draw procedure generally takes about 10-15 minutes.
Setting
The procedure is performed in a clinical laboratory, hospital, or outpatient clinic.
Personnel
- Phlebotomist or nurse for drawing the blood sample
- Laboratory technicians for analyzing the sample
Risks and Complications
- Minor pain or bruising at the puncture site
- Rare complications include fainting or hematoma
Benefits
Identifying antibodies can help in the accurate diagnosis and treatment of clotting disorders and autoimmune diseases. Results may be realized within a few days after the blood sample is analyzed.
Recovery
- Post-procedure care usually involves pressing on the site to prevent bleeding.
- Most people can resume normal activities immediately after the blood draw.
Alternatives
- Coagulation studies (e.g., prothrombin time, activated partial thromboplastin time)
- Other antibody tests, such as anti-cardiolipin or lupus anticoagulant tests
Patient Experience
During the blood draw, you may feel a small prick or discomfort. Some patients experience mild bruising or tenderness at the puncture site. Pain management is usually not necessary, and comfort measures involve gentle pressure and potentially a bandage.