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Elevated Lipoprotein(a)

ICD10CM code

Elevated Lipoprotein(a) (E78.41)

Name of the Condition

  • Elevated Lipoprotein(a)
  • Also referred to as high Lp(a), lipoprotein little a.

Summary

Elevated Lipoprotein(a) is a medical condition characterized by higher than normal levels of lipoprotein(a) in the blood. Lipoprotein(a) is a type of lipoprotein similar to LDL cholesterol, which can contribute to the buildup of plaques in blood vessels, increasing the risk of cardiovascular diseases.

Causes

The primary cause of elevated lipoprotein(a) levels is genetic predisposition. High levels are often inherited, and lifestyle factors do not significantly affect Lp(a) levels.

Risk Factors

  • Family history of high Lp(a) or cardiovascular disease.
  • Certain medical conditions, such as kidney disease, may lead to higher levels of Lp(a).
  • Generally unaffected by diet or lifestyle.

Symptoms

Elevated Lp(a) on its own may not produce symptoms. However, it can increase the risk of cardiovascular issues, which may present as:

  • Chest pain
  • Shortness of breath
  • Fatigue

Diagnosis

  • Blood Test: The only way to diagnose elevated Lp(a) is through a specific blood test measuring the concentration of lipoprotein(a) particles.

Treatment Options

  • Medications: Limited options specifically target Lp(a), but treatments for managing overall cholesterol levels might be recommended, such as statins or niacin.
  • Lifestyle Adjustments: While not directly affecting Lp(a) levels, maintaining a heart-healthy lifestyle can reduce overall cardiovascular risk.
  • Emerging Therapies: New treatments, such as specific Lp(a)-lowering drugs, are under research and may offer future options.

Prognosis and Follow-Up

  • The prognosis varies depending on individual cardiovascular risks and response to treatment.
  • Regular monitoring of cardiovascular health is important.
  • Periodic assessments of Lp(a) levels may be advised.

Complications

  • Increased risk of coronary artery disease.
  • Higher likelihood of stroke or heart attack if other risk factors are present.

    Lifestyle & Prevention

  • Maintain a healthy diet and exercise regularly to reduce general cardiovascular risk factors.
  • Avoid smoking and manage other health conditions such as hypertension or diabetes.

When to Seek Professional Help

  • If you have a family history of heart disease, consider screening for elevated Lp(a).
  • Seek medical advice if experiencing symptoms like chest pain or shortness of breath.

Additional Resources

Tips for Medical Coders

  • Ensure the code E78.41 is used specifically for elevated levels of lipoprotein(a), not for other types of cholesterol abnormalities.
  • Always verify the diagnosis with laboratory test results indicating high Lp(a) levels.
  • Avoid coding errors by distinguishing elevated Lp(a) from common hypercholesterolemia.

Medical Policies and Guidelines for Elevated Lipoprotein(a)

Related policies from health plans

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