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Cystatin C

CPT4 code

Name of the Procedure:

Cystatin C Test, Serum Cystatin C, CysC

Summary

The Cystatin C test is a blood test used to measure the level of cystatin C, a protein produced by cells in the body. This test helps assess kidney function and is often used as an alternative or complement to creatinine-based tests.

Purpose

The test primarily addresses the diagnosis and monitoring of kidney function and early detection of kidney disease. It aims to provide a more accurate assessment of kidney health, particularly in cases where creatinine-based tests may be less reliable.

Indications

  • Symptoms of kidney dysfunction: edema, fatigue, high blood pressure
  • Patients with a family history of kidney disease
  • Conditions known to affect kidney function: diabetes, hypertension, cardiovascular disease
  • Monitoring kidney function in patients on nephrotoxic medications

Preparation

  • Generally, no fasting is required.
  • Inform the healthcare provider of all medications and supplements being taken.
  • No specific pre-test diagnostics are typically needed.

Procedure Description

  1. Blood Sample Collection: A healthcare professional will draw a blood sample, typically from a vein in your arm.
  2. Laboratory Analysis: The blood sample is sent to a lab where the level of cystatin C is measured using specialized techniques.

No anesthesia or sedation is needed for this simple blood draw.

Duration

The blood draw takes only a few minutes. Results are generally available within a few days.

Setting

The test is typically performed in a hospital, outpatient clinic, or laboratory.

Personnel

  • Phlebotomist or nurse to draw the blood sample
  • Laboratory technician or medical technologist to analyze the sample
  • Physician to interpret the results

Risks and Complications

  • Minor risks include bruising or infection at the puncture site.
  • Rarely, patients may feel lightheaded or faint.

Benefits

  • Provides a more accurate assessment of kidney function than some other tests.
  • Early detection of kidney disease can lead to timely intervention and management.
  • Particularly useful for patients where creatinine levels may be influenced by other factors (e.g., muscle mass, diet).

Recovery

  • No recovery time is needed.
  • Patients can resume normal activities immediately after the blood draw.

Alternatives

  • Creatinine blood test: Less expensive but less accurate in certain populations.
  • Glomerular Filtration Rate (GFR) test: Often used in conjunction with creatinine measurement.
  • Urine albumin test: Used to detect protein in the urine as an indicator of kidney damage.

Patient Experience

  • Mild discomfort or pain from the needle stick.
  • Brief bruising or soreness at the puncture site, managed with a cold pack and over-the-counter pain relief if necessary.
  • Generally, minimal disruption to daily life.