This document addresses neutron beam radiation therapy. Radiobiologic principles suggest that neutron beam radiotherapy (NBT) is associated with a higher linear energy transfer (LET) compared with conventional photon or electrons resulting in a high radiation biological effect (RBE). Certain tumors seem to be more susceptible to the cytotoxic effects of neutrons, including salivary gland tumors. NBT or neutron beam radiation therapy is not to be confused with boron neutron capture therapy (BNCT) for cancer, which is not addressed within this document.

Position Statement

Investigational and Not Medically Necessary:

Neutron beam radiotherapy is considered investigational and not medically necessary for all indications.