This document addresses non-invasive measurement of advanced glycation end products (AGEs) in the skin via photospectroscopy. AGEs have been indicated as mediators of various vascular and cardiac complications in a wide variety of conditions, including diabetes, renal failure, and congestive heart failure.

Position Statement

Investigational and Not Medically Necessary:

Non-invasive measurement of advanced glycation end products (AGEs) in the skin is considered investigational and not medically necessary for all indications, including but not limited to diabetes, renal failure, and cardiac disease.