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Multiple myeloma not having achieved remission

ICD10CM code
#### Name of the Condition
- Multiple Myeloma Not Having Achieved Remission (ICD-10 Code: C90.00)
- Also known as active multiple myeloma.

#### Summary
Multiple myeloma is a type of blood cancer that affects plasma cells, a kind of white blood cell found in bone marrow. When multiple myeloma has not achieved remission, it means the disease remains active and has not responded successfully to treatment.

#### Causes
The exact cause of multiple myeloma is unknown, but it involves genetic mutations that lead to the uncontrolled growth of abnormal plasma cells. Environmental factors and previous infections may contribute to the development of the disease.

#### Risk Factors
- Age: Most common in individuals over 60.
- Gender: More prevalent in males.
- Family history of multiple myeloma.
- Exposure to radiation or certain industrial chemicals.
- Obesity.

#### Symptoms
- Bone pain, especially in the spine or chest
- Fatigue and weakness
- Frequent infections
- Weight loss
- Nausea
- Hypercalcemia (elevated calcium levels in the blood)

#### Diagnosis
- Blood tests to measure levels of blood cells, calcium, and proteins.
- Urine tests to identify abnormal proteins.
- Bone marrow biopsy to examine plasma cells.
- Imaging tests like X-rays, MRI, or CT scans to assess bone damage.

#### Treatment Options
- Chemotherapy helps kill or stop the growth of cancerous cells.
- Targeted therapy focuses on specific abnormalities in cancer cells.
- Immunotherapy boosts the body's immune response against cancer.
- Stem cell transplant replaces diseased bone marrow with healthy cells.
- Radiation therapy may relieve bone pain and reduce tumor size.

#### Prognosis and Follow-Up
The prognosis varies, with treatment often allowing for periods of management. Regular follow-ups are essential to monitor disease progression and adjust treatment plans as needed.

#### Complications
- Bone fractures or severe bone pain
- Kidney damage
- Anemia or severe fatigue
- Increased risk of infections

#### Lifestyle & Prevention
- Maintaining a healthy weight and diet.
- Regular exercise to enhance overall health.
- Avoiding exposure to known carcinogens.

#### When to Seek Professional Help
- Persistent or severe bone pain
- Symptoms of anemia, such as unusual fatigue
- Recurrent or severe infections

#### Additional Resources
- American Cancer Society: [cancer.org](https://www.cancer.org)
- International Myeloma Foundation: [myeloma.org](https://www.myeloma.org)

#### Tips for Medical Coders
- Ensure accurate documentation of the condition's active status when coding.
- Avoid confusing with codes indicating remission or relapsed/remitting states.
- Review patient history for confirmation of active disease status.

Medical Policies and Guidelines for Multiple myeloma not having achieved remission

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Therapeutic Apheresis
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