Name of the Procedure:

Injection, ifosfamide, 1 gram (J9208)

• Common Name: Chemotherapy Injection, Ifosfamide
• Technical Term: Intravenous Ifosfamide Administration

Summary

Injection of ifosfamide is a treatment process where a qualified healthcare professional administers the chemotherapy drug ifosfamide directly into a patient's bloodstream via an injection.

Purpose

• Medical Conditions: Primarily used to treat various types of cancer, including testicular cancer, lymphomas, sarcomas, and some types of lung cancer.
• Goals: To kill or slow the growth of cancer cells, potentially achieving remission or reducing tumor size to improve symptoms and quality of life.

Indications

• Symptoms/Conditions: Rapidly growing tumors, metastatic cancers, or recurrent cancer after initial therapies.
• Patient Criteria: Typically chosen for patients with cancers sensitive to ifosfamide, upon evaluation by an oncologist.

Preparation

• Pre-Procedure Instructions: Patients may need to undergo blood tests to assess kidney and liver function, hydrate adequately, and possibly adjust current medications.
• Diagnostic Tests: Blood tests, kidney function tests, and sometimes imaging studies to monitor the cancer.

Procedure Description

1. Setup: Patient is seated or lying comfortably. An intravenous (IV) line is placed in a vein.
2. Administration: Ifosfamide is administered slowly through the IV line. Hydration fluids may also be given to protect kidneys.
3. Monitoring: Continuous monitoring of vital signs and observation for any immediate reactions.
4. Completion: The IV line is removed after the medication is administered, and a bandage is applied to the injection site.

• Tools/Equipment: IV catheter, ifosfamide solution, IV infusion pump.
• Anesthesia/Sedation: Not typically required.

Duration

• The procedure typically lasts between 30 minutes to several hours, depending on the dosage and specific treatment regimen.

Setting

• Location: Hospital oncology department, outpatient clinic, or chemotherapy center.

Personnel

• Healthcare Professionals: Oncologist, chemotherapy nurse, sometimes a pharmacist for medication preparation.

Risks and Complications

• Common Risks: Nausea, vomiting, hair loss, low blood counts, fatigue.
• Rare Risks: Allergic reactions, kidney damage, bladder irritation, secondary cancers.
• Management: Supportive care, hydration, medication adjustments, and monitoring by the healthcare team.

Benefits

• Expected Benefits: Reduction in tumor size, relief of symptoms, potential remission.
• Timeline: Benefits may be realized in weeks to months, depending on individual response and treatment plan.

Recovery

• Post-Procedure Care: Patients may need anti-nausea medications, hydration, and rest.
• Recovery Time: Varies; most patients can resume daily activities within a day but may feel fatigued.
• Restrictions: Avoidance of unprotected exposure to infections, periodic blood tests, and follow-up appointments.

Alternatives

• Other Treatments: Surgery, radiation therapy, other chemotherapy drugs, targeted therapy, immunotherapy.
• Pros and Cons: Alternatives may have different efficacy, side effect profiles, or suitability based on the specific type of cancer and patient health status.

Patient Experience

• During the Procedure: Patients may feel a pinch from the IV insertion, mild discomfort at the injection site.
• After the Procedure: Fatigue, nausea, and other side effects may occur; managed with supportive medications and care.
• Pain Management: Anti-nausea medications, hydration, rest, and pain relief measures as needed.

This comprehensive outline helps provide a clear understanding of the injection of ifosfamide, a chemotherapy treatment, for both patients and healthcare providers.