Name of the Procedure:

• Common Name(s): Injection of ceftolozane and tazobactam
• Technical or Medical Terms: HCPCS Code J0695

Summary

This procedure involves injecting a combination of two antibiotics, ceftolozane and tazobactam, to treat bacterial infections. The injection contains 50 mg of ceftolozane and 25 mg of tazobactam.

Purpose

• Medical Conditions/Problems Addressed: Severe bacterial infections that are resistant to other antibiotics, particularly infections caused by multi-drug-resistant gram-negative bacteria.
• Goals/Expected Outcomes: To eliminate bacterial infections, alleviate symptoms, and prevent the spread of infection.

Indications

• Symptoms/Conditions Warranting the Procedure: Severe intra-abdominal infections, complicated urinary tract infections, and hospital-acquired bacterial pneumonia.
• Patient Criteria/Factors: Patients who have documented bacterial infections resistant to other antibiotics or who have failed other treatments.

Preparation

• Pre-Procedure Instructions: Patients may need to inform their healthcare provider about any allergies, especially to penicillin or beta-lactam antibiotics. No specific fasting or dietary restrictions are typically required.
• Diagnostic Tests/Assessments: Blood tests and cultures to identify the bacteria and determine antibiotic susceptibility.

Procedure Description

1. Patient is positioned comfortably to receive the injection.
2. The skin at the injection site is cleaned with an antiseptic wipe.
3. A sterile needle is used to administer the injection into a vein (intravenous injection) or muscle (intramuscular injection).
4. The injection is given slowly to ensure proper absorption and reduce discomfort.
5. The injection site is monitored for any immediate adverse reactions.

• Tools/Equipment Used: Sterile needle, syringe, antiseptic wipes.
• Anesthesia/Sedation Details: Generally, no anesthesia or sedation is required, though topical numbing agents might be used for comfort.

Duration

• Typical Duration: The injection process typically takes a few minutes. However, infusion times can vary if administered via an intravenous line.

Setting

• Where Performed: Hospital, outpatient clinic, or other healthcare facilities.

Personnel

• Healthcare Professionals Involved: Registered nurses or other qualified healthcare professionals administer the injection. Physicians prescribe and supervise the treatment plan.

Risks and Complications

• Common Risks: Pain at the injection site, redness, or swelling.
• Rare Risks: Severe allergic reactions, anaphylaxis, development of secondary infections, or antibiotic resistance.
• Management of Complications: Monitoring for adverse reactions and providing immediate medical intervention if required.

Benefits

• Expected Benefits: Effective treatment of severe bacterial infections, symptom relief, and prevention of further complications.
• Realization Timeline: Benefits can often be observed within a few days after starting the treatment but may vary based on the patient’s condition.

Recovery

• Post-Procedure Care/Instructions: Monitor the injection site for signs of infection or adverse reactions. Follow the complete antibiotic course as prescribed.
• Expected Recovery Time: Varies by individual and the severity of the infection; typically spans from a few days to a couple of weeks.
• Restrictions/Follow-Up Appointments: Patients may need follow-up appointments to assess the effectiveness of the treatment and make necessary adjustments.

Alternatives

• Other Treatment Options: Oral antibiotics, other intravenous antibiotics, or combination therapies.
• Pros and Cons: Alternatives may vary in effectiveness, side effects, and convenience. This specific combination (ceftolozane/tazobactam) is often used when other antibiotics have failed or are less effective.

Patient Experience

• During Procedure: Mild discomfort or pain at the injection site, which is usually brief.
• After Procedure: Patients might experience minor soreness at the injection site but can often resume normal activities shortly after. Pain management can include over-the-counter pain relievers if advised by the healthcare provider.